ID A0A1Q5EA80_9ACTN Unreviewed; 316 AA.
AC A0A1Q5EA80;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=AsnC family transcriptional regulator {ECO:0000313|EMBL:OKJ04906.1};
GN ORFNames=AMK18_06955 {ECO:0000313|EMBL:OKJ04906.1};
OS Streptomyces sp. CB01249.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703929 {ECO:0000313|EMBL:OKJ04906.1, ECO:0000313|Proteomes:UP000186839};
RN [1] {ECO:0000313|EMBL:OKJ04906.1, ECO:0000313|Proteomes:UP000186839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01249 {ECO:0000313|EMBL:OKJ04906.1,
RC ECO:0000313|Proteomes:UP000186839};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ04906.1}.
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DR EMBL; LISW01000001; OKJ04906.1; -; Genomic_DNA.
DR RefSeq; WP_073862074.1; NZ_LISW01000001.1.
DR AlphaFoldDB; A0A1Q5EA80; -.
DR OrthoDB; 3453230at2; -.
DR Proteomes; UP000186839; Unassembled WGS sequence.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 3.30.70.920; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR011008; Dimeric_a/b-barrel.
DR InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30154; LEUCINE-RESPONSIVE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30154:SF34; TRANSCRIPTIONAL REGULATOR AZLB; 1.
DR Pfam; PF01037; AsnC_trans_reg; 1.
DR Pfam; PF13404; HTH_AsnC-type; 2.
DR PRINTS; PR00033; HTHASNC.
DR SMART; SM00344; HTH_ASNC; 2.
DR SUPFAM; SSF54909; Dimeric alpha+beta barrel; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50956; HTH_ASNC_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000186839};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..66
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|PROSITE:PS50956"
FT DOMAIN 172..232
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|PROSITE:PS50956"
SQ SEQUENCE 316 AA; 34076 MW; 152D6610BAED7FBA CRC64;
MESVTLDALD LRLLHALQLD GRAPFSRIAE VLDVSDRTVA RRFGKLRAAG IARIAGVTNS
HRLGHAEWLV RLRVPPARST ALARALAHRP DTAWVAVLSS GTEIGCVFRV AGEGPAPLAA
LSRLPYVGHV EAHRVLRPVM ERRWSGRNLA LTDDQITALT PEPAADPTPV ELTDLDRRLL
PALAADGRAA YPDLARRIGW SESAVRRRLH ELRRMGVLQL DVEIDSGLFG FSVQCMLRLS
IAPGSLAQTA RALAEDAEAA FVGTMTGSHN LVAVAVCRDA AALDTYLTER VGTLGGVERV
ESALVTAYFK RAAPEG
//
