ID A0A1Q5FPG5_9ACTN Unreviewed; 416 AA.
AC A0A1Q5FPG5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Hyaluronate lyase {ECO:0000313|EMBL:OKJ22241.1};
GN ORFNames=AMK22_34480 {ECO:0000313|EMBL:OKJ22241.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ22241.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ22241.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ22241.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ22241.1}.
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DR EMBL; LIXJ01000049; OKJ22241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5FPG5; -.
DR STRING; 1703933.AMK22_34480; -.
DR OrthoDB; 417034at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR NCBIfam; TIGR02032; GG-red-SF; 1.
DR PANTHER; PTHR42685:SF22; CONDITIONED MEDIUM FACTOR RECEPTOR 1; 1.
DR PANTHER; PTHR42685; GERANYLGERANYL DIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:OKJ22241.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186318}.
SQ SEQUENCE 416 AA; 44616 MW; 584B8F3D5C62F3FA CRC64;
MGHWWDREQK HIVSSENADA VQEREESTVW DVVVVGGGPA GASAAYAAAV AGRRVLLLER
AELPRYKTCG GGIIGFSRDS LPPGFELPLR DRVHAVTFSL NGRLARTRRS KRMLFGLINR
PEFDAGLVEE AQKAGAELRT GATVTRVEQH GAAVPDRRTV AVVLAGGETV LARAVVGADG
SAGRIGAHVG VKLDQVDLGL EAEIPVPPTV AEDWAGRVLI DWGPMPGSYG WVFPKGDTLT
VGVISARGDG AGTKRYLEDF IARLGLAGFE PKISSGHLTR CRSDDSPLSR GRVLVCGDAA
GLLEPWTREG ISFALRSGRL AGEWAVRIAE SHDAVDARRQ ALNYAFAIKA GLGVEMGVGR
RMLKLFERRP GVLHAVLTGF RPAWNAFAGV TRGTTSLAEL VRTHPLAQRA LSMMDR
//
