ID A0A1Q5G1R4_9ACTN Unreviewed; 676 AA.
AC A0A1Q5G1R4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Ricin-type beta-trefoil lectin domain protein {ECO:0000313|EMBL:OKJ26510.1};
GN ORFNames=AMK22_31740 {ECO:0000313|EMBL:OKJ26510.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ26510.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ26510.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ26510.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ26510.1}.
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DR EMBL; LIXJ01000035; OKJ26510.1; -; Genomic_DNA.
DR RefSeq; WP_073791029.1; NZ_LIXJ01000035.1.
DR AlphaFoldDB; A0A1Q5G1R4; -.
DR STRING; 1703933.AMK22_31740; -.
DR OrthoDB; 9806701at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR039514; 6GAL-like.
DR InterPro; IPR039743; 6GAL/EXGAL.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR42767; ENDO-BETA-1,6-GALACTANASE; 1.
DR PANTHER; PTHR42767:SF1; GLYCO_HYDR_30_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14587; Glyco_hydr_30_2; 1.
DR Pfam; PF14200; RicinB_lectin_2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Lectin {ECO:0000313|EMBL:OKJ26510.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186318};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..676
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013293226"
FT DOMAIN 540..673
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
SQ SEQUENCE 676 AA; 72930 MW; C397C32D50AF6773 CRC64;
MPRRTHSRRF LGAASMTALA TGAALLSVPA PPALADTATA SVTVQPDPSY KQDKFEGWGT
SLVWFANATG DYPKEIREKL ADLLFDDDGL ALNIARYNIG GGNAPDVKDY LRPGGAVEGW
WKAPAGTTRA DTDWWNPDDP AHWNDKADAT QRWWAKRIKN DIDHWETFSN SPPWFMTVSG
YVSGGFNAGV DQLKESSVDD FAAYLAGATK RLEKSEGIKV DTIDPFNEPI GHWGTRLDAD
GNPVARQEGA DIGPELQQKV VAALEPALKK AKVKAGISAM DESTPWGFAT TWNSYSQASK
DLVGRMNVHT YNTGQRTTVR DLAKAADKPL WMSEVEGDWG DGQSFTDMRP GLGLAQHIVN
DLRELEPKAW VFWQPVEDYD NMKPGGEFAK GGNWGSVQIP FSCTSADTLK TCPIYTNTKF
DTARNFTHFI KPGDSLIKVD DTSSAAAVTK NGKGASLVHV NSTTAPRAVT IDLSKFGEIK
RDAAVTPTVT DAAGKLVKQA PVKVVDGKAT FTVPAQSVTS FAVKGVSGVA KNASLFSTGK
SYTMTGVQSG KAMTVDANGT NLVINSTNST VAQEWRLEAK HGTTGNRQRY VFANPAEGKR
LTVRDNVPVI EADTGERNPA AEWILSTTGD GTWTLVNVAT GQLLEVGGQA TNEGAAVTTW
QANSGSNQRW RFTEVS
//
