ID A0A1Q5GJM8_9ACTN Unreviewed; 323 AA.
AC A0A1Q5GJM8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Aminoglycoside phosphotransferase {ECO:0000313|EMBL:OKJ32801.1};
GN ORFNames=AMK22_21770 {ECO:0000313|EMBL:OKJ32801.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ32801.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ32801.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ32801.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ32801.1}.
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DR EMBL; LIXJ01000016; OKJ32801.1; -; Genomic_DNA.
DR RefSeq; WP_073787711.1; NZ_LIXJ01000016.1.
DR AlphaFoldDB; A0A1Q5GJM8; -.
DR STRING; 1703933.AMK22_21770; -.
DR OrthoDB; 4558647at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186318};
KW Transferase {ECO:0000313|EMBL:OKJ32801.1}.
FT DOMAIN 45..262
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 323 AA; 33622 MW; 0BB514FF623DB0B3 CRC64;
MTTAVVRALG ALAHRAAHPP SGTACACPPP KTLADRADGT VVRSGPVVAK AHAPGTPVPD
LLTRIALADH PRLTGILLAP LRPRPDEASA VLHGRPVTLW PHGEPVDPDD PDAAPWGEAA
ALLAALHRTP PPSSLALPPM RGPAKAALAV ARMRAARPDD PATAPVLAAW LRLPAWARGE
ATPPAHRARF LCHGDLHLGQ LVRHPAPQGP WTLIDIDDAG LGDPAWDLAR PAAWYAAGLL
PPDVWLRFLD SYRAAGGPAV PAGGDPWPEL DVPARALTVQ TAALAYAKSA AEGRAPDEVE
RAVIDACVRI ASLPSELAAE HTS
//
