ID A0A1Q5GR52_9ACTN Unreviewed; 294 AA.
AC A0A1Q5GR52;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Bile acid:sodium symporter {ECO:0000313|EMBL:OKJ35046.1};
GN ORFNames=AMK22_17635 {ECO:0000313|EMBL:OKJ35046.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ35046.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ35046.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ35046.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ35046.1}.
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DR EMBL; LIXJ01000011; OKJ35046.1; -; Genomic_DNA.
DR RefSeq; WP_073786289.1; NZ_LIXJ01000011.1.
DR AlphaFoldDB; A0A1Q5GR52; -.
DR STRING; 1703933.AMK22_17635; -.
DR OrthoDB; 3576174at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR004710; Bilac:Na_transpt.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR10361:SF28; RH04535P; 1.
DR PANTHER; PTHR10361; SODIUM-BILE ACID COTRANSPORTER; 1.
DR Pfam; PF01758; SBF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186318};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 294 AA; 29333 MW; D05AB54603E289D6 CRC64;
METLHLLFNA ITVIFIAATM FAAGLGTTVA ALRSVFTNIP LLVLALLANL VVVPLLSWGI
GMLFGLPAAA FIALVLAASS PGGPFGAKLA MVQGGDVVAG AAMQVLLATI GSLTFAPTAN
GILSASGVGQ GVSLDIAALV GTVALLQLLP FAVGLLLRHC ATPTARAWHP PATTVSNVTF
LIVLAGMLLG NWHDVLALLG SLALLAGFVL AAAAFAAGTL LTTGPPVRRT TMGGIAAVRN
AGPALAAIGI AFSGQPAILG ALAAVLLSGL AAALPIAAVL NSRRNRPPTT RRAR
//
