ID A0A1Q5GYR9_9ACTN Unreviewed; 325 AA.
AC A0A1Q5GYR9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Terpene synthase {ECO:0000256|RuleBase:RU366034};
DE EC=4.2.3.- {ECO:0000256|RuleBase:RU366034};
GN ORFNames=AMK22_12690 {ECO:0000313|EMBL:OKJ37565.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ37565.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ37565.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ37565.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|RuleBase:RU366034};
CC -!- SIMILARITY: Belongs to the terpene synthase family.
CC {ECO:0000256|RuleBase:RU366034}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ37565.1}.
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DR EMBL; LIXJ01000007; OKJ37565.1; -; Genomic_DNA.
DR RefSeq; WP_073784595.1; NZ_LIXJ01000007.1.
DR AlphaFoldDB; A0A1Q5GYR9; -.
DR STRING; 1703933.AMK22_12690; -.
DR OrthoDB; 3676909at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR034686; Terpene_cyclase-like_2.
DR PANTHER; PTHR35201; TERPENE SYNTHASE; 1.
DR PANTHER; PTHR35201:SF4; TERPENE SYNTHASE; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01020; Terpene_Cyclase_Like_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU366034};
KW Magnesium {ECO:0000256|RuleBase:RU366034};
KW Metal-binding {ECO:0000256|RuleBase:RU366034};
KW Reference proteome {ECO:0000313|Proteomes:UP000186318}.
SQ SEQUENCE 325 AA; 37054 MW; 4FBA4B84DA9FD2F7 CRC64;
MPFESTGCNP GIEETRKVAW EWAESQGLVL SPTARKKMIR TRPELWISLI FPTASQQHLD
LFCQWLFWAF LVDDEFDDGP AGRDPRMCEA AIDRLVTVLD GGPPRGAMEH ALVDLRERTY
RGRPAHWLRQ FRRDTVAWLW TYCAEAVERA AGQVPTREDF VRHRRDSVAM QPFLDLHEIT
AGIDLPESAR ALPAYIALRN AVTDHSGLCN DICSFEKEAR LGYEHNAVRL IQRERGCTLQ
EAVDEAGAQL GGVAERVRRA ERELVEQIAA AGIEGSTRVA LERCVRDYRG LVRGDFDYHA
RAERYTRPDL VEIDDRETLS RFFAA
//
