ID A0A1Q5H5K2_9ACTN Unreviewed; 338 AA.
AC A0A1Q5H5K2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=HTH deoR-type domain-containing protein {ECO:0000259|PROSITE:PS51000};
GN ORFNames=AMK22_11275 {ECO:0000313|EMBL:OKJ40099.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ40099.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ40099.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ40099.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ40099.1}.
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DR EMBL; LIXJ01000005; OKJ40099.1; -; Genomic_DNA.
DR RefSeq; WP_073784021.1; NZ_LIXJ01000005.1.
DR AlphaFoldDB; A0A1Q5H5K2; -.
DR STRING; 1703933.AMK22_11275; -.
DR OrthoDB; 3171994at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001034; DeoR_HTH.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR028349; PafC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR026881; WYL_dom.
DR PANTHER; PTHR34580; -; 1.
DR PANTHER; PTHR34580:SF6; HTH DEOR-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08279; HTH_11; 1.
DR Pfam; PF13280; WYL; 1.
DR PIRSF; PIRSF016838; PafC; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51000; HTH_DEOR_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186318};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..62
FT /note="HTH deoR-type"
FT /evidence="ECO:0000259|PROSITE:PS51000"
SQ SEQUENCE 338 AA; 37430 MW; 2F8C183BF4E7CFD5 CRC64;
MNRQQRLLAM LAALQARRRT TANELAAEFG VSVRTVMRDV EALAAAEVPV FTERGRYGGI
VLLPGTQLDV SRLSDTETEL LTVLGIDLVQ ARKLGMEAAA RSATDKLTAR GTPQRRAASQ
RSDLIPLAEV VAVDHRAWFV PDEDEEADIA SLTRDLRRGR RLRVRYRRSG TRRHRPTVVD
PYGVLLRGGR WYLVADTDGE PRMYALSRLA CWEVLDEPRI LRPNTTLTEL AGTLGAGLED
ARDVVVTVRL DADRLDIAKR ILGKRLLSTE TTDANADADT DADADGTVLV RVGYDRLDGV
RQLLQFSDHF EVVDPPAARE LVARLAGAIT LRHRTPSP
//
