ID A0A1Q5HA13_9ACTN Unreviewed; 298 AA.
AC A0A1Q5HA13;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:OKJ41694.1};
GN ORFNames=AMK22_09770 {ECO:0000313|EMBL:OKJ41694.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ41694.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ41694.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ41694.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ41694.1}.
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DR EMBL; LIXJ01000004; OKJ41694.1; -; Genomic_DNA.
DR RefSeq; WP_073783443.1; NZ_LIXJ01000004.1.
DR AlphaFoldDB; A0A1Q5HA13; -.
DR STRING; 1703933.AMK22_09770; -.
DR OrthoDB; 9783813at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR PANTHER; PTHR42659:SF1; BLR6160 PROTEIN; 1.
DR PANTHER; PTHR42659; XANTHINE DEHYDROGENASE SUBUNIT C-RELATED; 1.
DR Pfam; PF00941; FAD_binding_5; 1.
DR SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186318}.
FT DOMAIN 4..178
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 298 AA; 30305 MW; 456EDB38955E47ED CRC64;
MTTHAPQATQ SVTLPASLDE AVAALGAMPA AVPVAGGTDL MSAVNKGLLR PSGLVGLGRI
SELRGWHYQD GHALLGAGLT HARMGRPDFA ALIPALAAAA RAAGPPQIRN AGTLGGNIAT
AAPTGDSLPV LAALEADLVI AGPNGTRREI PVSHLLAGRD MLEPAELIGF VRVPLLHAPQ
VFLKATGRTG PGRATASVAI VLDPARRGVR CAVGAIAPMP LRPLEAEHWI ASLIDWDGAR
GLAPEALAAF GEYVAAACIP DQAPPVEGGE APPLPPAVLH LRRTVAALAR RALGRALS
//
