ID A0A1Q5HD48_9ACTN Unreviewed; 664 AA.
AC A0A1Q5HD48;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Inositolphosphotransferase Aur1/Ipt1 domain-containing protein {ECO:0000259|Pfam:PF14378};
GN ORFNames=AMK22_05235 {ECO:0000313|EMBL:OKJ42742.1};
OS Streptomyces sp. CB01580.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703933 {ECO:0000313|EMBL:OKJ42742.1, ECO:0000313|Proteomes:UP000186318};
RN [1] {ECO:0000313|EMBL:OKJ42742.1, ECO:0000313|Proteomes:UP000186318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01580 {ECO:0000313|EMBL:OKJ42742.1,
RC ECO:0000313|Proteomes:UP000186318};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 87 family.
CC {ECO:0000256|ARBA:ARBA00024033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ42742.1}.
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DR EMBL; LIXJ01000003; OKJ42742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5HD48; -.
DR STRING; 1703933.AMK22_05235; -.
DR OrthoDB; 5241565at2; -.
DR Proteomes; UP000186318; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR CDD; cd03386; PAP2_Aur1_like; 1.
DR InterPro; IPR026841; Aur1/Ipt1.
DR InterPro; IPR018584; GT87.
DR PANTHER; PTHR31310; -; 1.
DR PANTHER; PTHR31310:SF7; PA-PHOSPHATASE RELATED-FAMILY PROTEIN DDB_G0268928; 1.
DR Pfam; PF09594; GT87; 1.
DR Pfam; PF14378; PAP2_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186318};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 73..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 433..614
FT /note="Inositolphosphotransferase Aur1/Ipt1"
FT /evidence="ECO:0000259|Pfam:PF14378"
SQ SEQUENCE 664 AA; 71571 MW; 99D61D2A6389DB28 CRC64;
MLWLVVAALA VRQVAAVLRR PPGERLADLE TWIGDNGVLH VTGSLYDSDR FTGTPFAGLV
LKPLTRAAEQ SLGVVWTFGS LLLVVALGVV AARALPGPVA RRTSLLAAPV AISLLMLSLP
VRNAFHLGQT SIIPVLLVLL ACFAVRGERA SGLLIGVAAA LQPTVLLFAV LLLFTGRRRA
AVTGGVTFAA CTALAWAAMP HDSWTYWVHH VAGAGLGENA DSLANQSLHG ALLRFGLTGP
LEIALFVVLA AVVCWFGLRR AVRYAHDGQL LLAVAVTGCV AVAVSPTAWQ HQLLWVLLAV
VGRVGKRASD RLMWPTVVVL VLTLPAKMLL PNMAVVVPVR DNVLLITALG AACAVPFLPR
TSPYWRDPVP TDHAAPVAAR WSRIPLLPFW RRVLSRPNLL LELLLIRVVY SAYSQVRLAA
TAGRDTAERH GTQVHSLEQW LHIDIEHWAN HAVVEIDWLR DFFDFYYTSF HFIVPLTILG
VLYVRRPADY RWVRSSIGFT TVLALVGFWL YPLAPPRLMP GLGFIDTVHG VQDFAKPDYG
SLTSVTNQYA AMPSLHFGWS LWCGVVIVML APKPWMKALG LLHPLFTVSA IVATANHWVL
DAVGGAAVVA LGFGLTYALS GPRKLRAPAV PAAAKPLDDL VDGAPPGQVG DAVGGSHGQG
VFRK
//
