ID A0A1Q5I0I7_9ACTN Unreviewed; 359 AA.
AC A0A1Q5I0I7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:OKJ50601.1};
GN ORFNames=AMK29_33115 {ECO:0000313|EMBL:OKJ50601.1};
OS Streptomyces sp. CB02261.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703940 {ECO:0000313|EMBL:OKJ50601.1, ECO:0000313|Proteomes:UP000186742};
RN [1] {ECO:0000313|EMBL:OKJ50601.1, ECO:0000313|Proteomes:UP000186742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02261 {ECO:0000313|EMBL:OKJ50601.1,
RC ECO:0000313|Proteomes:UP000186742};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ50601.1}.
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DR EMBL; LIVX01000014; OKJ50601.1; -; Genomic_DNA.
DR RefSeq; WP_073819884.1; NZ_LIVX01000014.1.
DR AlphaFoldDB; A0A1Q5I0I7; -.
DR OrthoDB; 3249147at2; -.
DR Proteomes; UP000186742; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR038727; NadR/Ttd14_AAA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR37512:SF1; AAA_28 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37512; TRIFUNCTIONAL NAD BIOSYNTHESIS/REGULATOR PROTEIN NADR; 1.
DR Pfam; PF13521; AAA_28; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
FT DOMAIN 9..135
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT DOMAIN 156..333
FT /note="NadR/Ttd14 AAA"
FT /evidence="ECO:0000259|Pfam:PF13521"
SQ SEQUENCE 359 AA; 39760 MW; 5DEF174E16A333AE CRC64;
MKRHGHGLVL GKFYPPHAGH HHLVETALAR CERLTVLVCA SSVESVPLEE RVAWMREIHP
DALVVGAVDD IPVDLHDPDV WDAHMAVFRS AVREPVDAVF TSEPYGEELA RRFGAESVCV
DPGRTRFPVS GTAVRADPAG CWDFLKAPVR AALTRRVVVL GAESTGTTTM ALALTDHYRR
RGGVWARTRY VPEYGREYSE LKLAELRAEH PGATWADVAF HSSDFPVIAQ RQAELEEEAA
RDGSPVLFCD TDAFATTIWH ERYMGTASPA TGEVAALGRQ HLWLLTDHRG VDFEDDGLRD
GEHLRPWMTA RFLTQLAHTG RRTAVLSGPH EERLAAAVAA VDALLAEGWH LTDPLPERR
//
