ID A0A1Q5I6D8_9ACTN Unreviewed; 436 AA.
AC A0A1Q5I6D8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Phenylacetate--CoA ligase {ECO:0000313|EMBL:OKJ52657.1};
GN ORFNames=AMK29_31095 {ECO:0000313|EMBL:OKJ52657.1};
OS Streptomyces sp. CB02261.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703940 {ECO:0000313|EMBL:OKJ52657.1, ECO:0000313|Proteomes:UP000186742};
RN [1] {ECO:0000313|EMBL:OKJ52657.1, ECO:0000313|Proteomes:UP000186742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02261 {ECO:0000313|EMBL:OKJ52657.1,
RC ECO:0000313|Proteomes:UP000186742};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ52657.1}.
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DR EMBL; LIVX01000012; OKJ52657.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5I6D8; -.
DR OrthoDB; 580775at2; -.
DR Proteomes; UP000186742; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR028154; AMP-dep_Lig_C.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43845; BLR5969 PROTEIN; 1.
DR PANTHER; PTHR43845:SF1; BLR5969 PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF14535; AMP-binding_C_2; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:OKJ52657.1}.
FT DOMAIN 91..283
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 339..430
FT /note="AMP-dependent ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14535"
SQ SEQUENCE 436 AA; 49014 MW; 89328CB7FAD2DF08 CRC64;
MEYWNPKAET MPRHELEEWQ WRRLQRALHN ARARSPFWRD RLPGDITSME DYARRVPLLH
KADLLAAEQQ APPYGTWPSI DPARGIRHHQ TSGTSGNPPV RTIDTAGDWT WSTDTFCTAL
YAMGVRPHHK GMVAFGYGLF MGFWGMHYGL ERMGCTVVPA GGLDSRTRIK LLVDYGIEVV
GLTPSYAMRL IETAREMGID LAKEANVEII LAGAEPRSKF TTRTIEEAFG ARVFNAAGTT
EFGGVFMFEC PSRRGACHII EPSTIEEVLH PETKLPVGYG EEGVRVTTGL SREGMQLFRH
WTEDVVVKQP AAACGCGRTW DFYDGGIIRR VDDMRKIRGV SVTPVMIEDV VRGFDEVSEF
STSISSVRGL DTVFVRVEPR HVPGGDVTTL TRRIAEEFKR EIGIRPEVEL APEGSLPRQE
WKAARLRDER ALVSQP
//
