ID A0A1Q5J055_9ACTN Unreviewed; 483 AA.
AC A0A1Q5J055;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=AMK29_21420 {ECO:0000313|EMBL:OKJ62665.1};
OS Streptomyces sp. CB02261.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703940 {ECO:0000313|EMBL:OKJ62665.1, ECO:0000313|Proteomes:UP000186742};
RN [1] {ECO:0000313|EMBL:OKJ62665.1, ECO:0000313|Proteomes:UP000186742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02261 {ECO:0000313|EMBL:OKJ62665.1,
RC ECO:0000313|Proteomes:UP000186742};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ62665.1}.
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DR EMBL; LIVX01000006; OKJ62665.1; -; Genomic_DNA.
DR RefSeq; WP_073815478.1; NZ_LIVX01000006.1.
DR AlphaFoldDB; A0A1Q5J055; -.
DR OrthoDB; 3199405at2; -.
DR Proteomes; UP000186742; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235}.
FT DOMAIN 5..317
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 355..467
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 483 AA; 50366 MW; DEF908B96052A1BF CRC64;
MSTSGPVVST ARGPVRGERR ADGSLRFLGI PYARPPVGDL RFAAPVPPEP WSEPLDATRY
GPTAQRRPFA EVTTIPEPSV PGAGILNLNV FTPSVAPSAA LPVLVWIHGG GYVAGSAASP
WYDGAAFNRD GVVLVSLGYR LGIEGFLHLE DAPDNRGVRD WVAALAWVRD NIAAFGGDPA
KVTVAGQSAG GGAVQTLLAC PAARGLFRGA LSVSGAVPRP DGPEVARAAS LLLTSRTGVP
ATAAALRDLG DDELLALQDR LAEPGPDREG LPPLLALAPF ADGELIPRPA LDALTTGDAG
ADVPLMLGFT AHEFTMFPGP GPEGPPLPVL LGGLGLDPAK ADAFAEAYAK DGAERLFGQA
LTDATFRAPN LAVADARAAR GRPTWLYEFA WRSPVVGLAV HCLDLPFAFD LLDAEGVTAA
AGEAPPRVLA DALHRAWVAF VTHQDPGADW PRYTPEGRAT MIWDAEPRIE ADPLGPVRAL
WLG
//
