ID A0A1Q5JC52_9ACTN Unreviewed; 654 AA.
AC A0A1Q5JC52;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OKJ66914.1};
GN ORFNames=AMK29_11415 {ECO:0000313|EMBL:OKJ66914.1};
OS Streptomyces sp. CB02261.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703940 {ECO:0000313|EMBL:OKJ66914.1, ECO:0000313|Proteomes:UP000186742};
RN [1] {ECO:0000313|EMBL:OKJ66914.1, ECO:0000313|Proteomes:UP000186742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02261 {ECO:0000313|EMBL:OKJ66914.1,
RC ECO:0000313|Proteomes:UP000186742};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the YccS/YhfK family.
CC {ECO:0000256|ARBA:ARBA00043993}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ66914.1}.
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DR EMBL; LIVX01000003; OKJ66914.1; -; Genomic_DNA.
DR RefSeq; WP_073811412.1; NZ_LIVX01000003.1.
DR AlphaFoldDB; A0A1Q5JC52; -.
DR OrthoDB; 3816110at2; -.
DR Proteomes; UP000186742; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR049453; Memb_transporter_dom.
DR InterPro; IPR032692; YccS_N.
DR PANTHER; PTHR30509:SF9; INNER MEMBRANE PROTEIN YCCS; 1.
DR PANTHER; PTHR30509; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED; 1.
DR Pfam; PF12805; FUSC-like; 1.
DR Pfam; PF13515; FUSC_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 92..256
FT /note="Integral membrane protein YccS N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12805"
FT DOMAIN 365..486
FT /note="Integral membrane bound transporter"
FT /evidence="ECO:0000259|Pfam:PF13515"
SQ SEQUENCE 654 AA; 69151 MW; E2172562B6A039D5 CRC64;
MARPAGSVRL SPPAWLTAGL KPAPAPIPWA AALRAAVALA APLAVGLAAG QPAYGALVSM
GALSGVIGDT ADAYRMRVFN IAVPQLFGAV GVTLGTLVFG HGWLAVAVLT LVALVSGMIS
SIGAVASVSG LLLLLNSVVG AGLPMPDPWW KAPLLLTLGG LFVLVLTLLG WPLRRAAPER
AAVAATYRAV AELYEATGSS AYDEKRHAVT ASLNHSYDLI LARRARQHGR APSLVRLLAQ
LNVVIPLAEA APAAHLRAQL YGPLSGAIPA TVRQLADAVE ESRTGTPVLD LPTPERPAEK
AVDHALRHAA AVVHQAEPDP HNVDDRLGRP AALRVRARRT TRAVLFSGAS WRYGLRLALC
IGLAQALVSL IAVPRSYWVA LTVTFVLKPD FGSVFSRAVL RALGTAAGLL LAALVLAEVP
RGWWDVPVMC VLAALIPVFS AKGYAFQTAA ITPVILLLSD TLNQQGFGLV MPRLYDSLIG
CGIALVAGYL LWPESWHTRI GDRLADAVAD TADYVALAFA EVTAGQGDQG TRLRARRKLY
RDLSTVRSEF QRALTEPPPT GARAAAWWPL VVAVERIVDA TTAARIRVDH GAPDPDPAEV
TAVERELREL ADGLRDTDTL VAVRTELPGD ETGVLEPLRQ EVRAARAIAG PDLR
//
