ID A0A1Q5JCE3_9ACTN Unreviewed; 224 AA.
AC A0A1Q5JCE3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Sortase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMK29_11850 {ECO:0000313|EMBL:OKJ66989.1};
OS Streptomyces sp. CB02261.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703940 {ECO:0000313|EMBL:OKJ66989.1, ECO:0000313|Proteomes:UP000186742};
RN [1] {ECO:0000313|EMBL:OKJ66989.1, ECO:0000313|Proteomes:UP000186742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02261 {ECO:0000313|EMBL:OKJ66989.1,
RC ECO:0000313|Proteomes:UP000186742};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ66989.1}.
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DR EMBL; LIVX01000003; OKJ66989.1; -; Genomic_DNA.
DR RefSeq; WP_073811596.1; NZ_LIVX01000003.1.
DR AlphaFoldDB; A0A1Q5JCE3; -.
DR OrthoDB; 5242879at2; -.
DR Proteomes; UP000186742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd05830; Sortase_E; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR023365; Sortase_dom-sf.
DR InterPro; IPR042003; Sortase_E.
DR NCBIfam; NF033747; class_E_sortase; 1.
DR NCBIfam; TIGR01076; sortase_fam; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 122
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 191
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 224 AA; 24830 MW; C0F7496A65D28964 CRC64;
MARVRNRIAG IISLFGELLI TAGVVLGLFV VYSLWWTNVL ADRAADQDGA QVRDRWADGP
GALDTKDGIG FLHVPAMGDD EILVKQGTTS AILNNGVAGY YTDPIKSALP QDKQGNFTLA
AHRDGHGAKF HNIHKLKTGD AIVFESKDTW YVYKVYKSLP QTTKYNVDVL QPVPKESGRT
KPGRFITLTT CTPMYTSDYR YIVWGELERT EKVDRARTPP AELG
//
