ID A0A1Q5JKS4_9ACTN Unreviewed; 1251 AA.
AC A0A1Q5JKS4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ABC transporter {ECO:0000313|EMBL:OKJ69895.1};
GN ORFNames=AMK29_04310 {ECO:0000313|EMBL:OKJ69895.1};
OS Streptomyces sp. CB02261.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703940 {ECO:0000313|EMBL:OKJ69895.1, ECO:0000313|Proteomes:UP000186742};
RN [1] {ECO:0000313|EMBL:OKJ69895.1, ECO:0000313|Proteomes:UP000186742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02261 {ECO:0000313|EMBL:OKJ69895.1,
RC ECO:0000313|Proteomes:UP000186742};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ69895.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIVX01000001; OKJ69895.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5JKS4; -.
DR OrthoDB; 9806127at2; -.
DR Proteomes; UP000186742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18543; ABC_6TM_Rv0194_D1_like; 1.
DR CDD; cd18546; ABC_6TM_Rv0194_D2_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 684..705
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 717..738
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 794..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..842
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 903..927
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..315
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 348..582
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 685..967
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1001..1241
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1251 AA; 134674 MW; 25B236849AFCA4F3 CRC64;
MGQKQASDGQ AAADGQQGWA RRLSGYAWRY KANVILALGS SLVGMGVLAL VPLVTKVIID
DVIGTKTRDL GVWTGLLIGA AVLVYVLTYV RRYYGGRLAL DVQHDLRTDM FATITRLDGR
RQDELSTGQV VGRATSDLQL IQGLLFMLPM TIGNVLLFLI SLAVMAWLSI PLTLVALAVA
PALWFIAKRS RTRLHPATWH AQQQAAVVAG VVDGAVTGVR VVKGFGQEDQ ETGKIREAGR
KLFAGRLRTI RLNSKYTPAL QAVPALGQVA VLALGGWLAY RGEITLGTFV AFSAYLASLV
GPVRMLAMVL TVGQQARAGV DRVLDLIDTE PVIQDGTKEL PADAPATVEF DDVSFAYDEG
RPVLDGFSLE IRPGETVAVV GASGSGKSTV SLLLPRFYDV SHGAVLVGGH DVRELTLDSL
RAAVGLVPED SFLFSDTVRA NIAYGLPEAT QEQIETAARA AQADRFIAEL PDGYDTKVGE
HGLTLSGGQR QRVALARAIL TDPRLLLLDD ATSAVDAKVE HEIHEALKSV MAGRTTLLIA
HRRSTLNLAD RIAVLDDGRL ADIGTHAELE ERSPLFRRLL TDPEELGAVS PGHVTPPEVP
EDRTLRAELD AEFDAERGIT PALWVRDETA GRESPAPGAT PELLAAVEAL PPAVDTPDID
EARAVAPEDT YGLRRLLRGF GVPLLISLGL VALDAGMGLL LPVLIRHGID EGVNRLAIGA
VWAASLLALV TVLVQWVAQT AETRMTGRTG ERVLYALRLK IFAQLQRLGL DYYERELTGR
IMTRMTTDVD ALSTFLQTGL VTAFVSVVTF FGIMVALLVL DLQLALVVFA TLPVLAVATY
FFRRSSVKAY ELARERISVV NGDLQESVSG LRIVQAFRRE RSGAARFAER SDSYRQARVR
GQWLISIYFP FVTLLSSAAA AAVLIVGANR IEAGTLTTGA LVAYLLYIDL FFAPVQQLSQ
VFDGYQQAAV SLKRMQELLQ EPTSTAAADA PLDVLSLRGE IAFEDVSFAY GGEDGTDKEE
TALTGIDLRI PAGQTVAFVG ETGAGKSTLV KLVARFYDPT GGRVTADGTD LRDLDLTAYR
HRLGVVPQEA YLFAGTVRDA IAYGRPEATD AEVEAAARAV GAHEMIATLD GGYLHEVAER
GRNLSAGQRQ LIALARAELV DPDVLLLDEA TAALDLATEA QVNLATDRLA GRRTTLVVAH
RLTTAARADR VIVMDHGRVA EDGTHEELLA LGGRYASLWS TFIGEAEPER V
//
