ID A0A1Q5JMZ3_9ACTN Unreviewed; 440 AA.
AC A0A1Q5JMZ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Chorismate-binding protein {ECO:0000313|EMBL:OKJ70707.1};
GN ORFNames=AMK31_35875 {ECO:0000313|EMBL:OKJ70707.1};
OS Streptomyces sp. TSRI0107.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703942 {ECO:0000313|EMBL:OKJ70707.1, ECO:0000313|Proteomes:UP000185813};
RN [1] {ECO:0000313|EMBL:OKJ70707.1, ECO:0000313|Proteomes:UP000185813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0107 {ECO:0000313|EMBL:OKJ70707.1,
RC ECO:0000313|Proteomes:UP000185813};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ70707.1}.
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DR EMBL; LIVZ01000019; OKJ70707.1; -; Genomic_DNA.
DR RefSeq; WP_073945064.1; NZ_LIVZ01000019.1.
DR AlphaFoldDB; A0A1Q5JMZ3; -.
DR STRING; 1703942.AMK31_35875; -.
DR OrthoDB; 3518032at2; -.
DR Proteomes; UP000185813; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR019996; Salicylate_synthase.
DR NCBIfam; TIGR03494; salicyl_syn; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF48; ISOCHORISMATE SYNTHASE MENF; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 4: Predicted;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000185813}.
FT DOMAIN 172..427
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 440 AA; 47339 MW; BD5B70B6FD4EB7CE CRC64;
MLRYRCAETE LPGDPVPWAT TLAESGLFDQ YVIYERDGDC WFAGGALAEI VVNRSEVRAR
VLAAESTAPV GPYPLRQVHR LLGESGIEGW RAYGWMAYEF AHLHAGRLDR AGDADLLHLI
VPHTEVRLRR GTAVVRGADR ETVDALLALL TAPPAERPVA APRPVDVTEG AADYPGLVAR
AVDEIRAAAT GLQKVILSRS VPVPFPVDFV GTYLHGRAHN TPARSFLLRL GGRRVAGFSP
ETVVEVGADG HLVTQPLAGT RARGLGERED ERLRAELLAD PKEISEHVLS VKLAEEELAT
VCRPGSVSVR ELLTVRQRGS VQHLGSSVHG RLGDDATCWD ALRALFPAVT ASGIPKSQAY
DCIARLEDGP RGVYSGAVLM AAADGELDAA LVLRSLFEQD GRTWLRAGAG ILAGSTPARE
LEETCEKLRS VAPYLVPAEG
//
