ID A0A1Q5JQ13_9ACTN Unreviewed; 618 AA.
AC A0A1Q5JQ13;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Toxic cation resistance protein {ECO:0000313|EMBL:OKJ71373.1};
GN ORFNames=AMK31_34750 {ECO:0000313|EMBL:OKJ71373.1};
OS Streptomyces sp. TSRI0107.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703942 {ECO:0000313|EMBL:OKJ71373.1, ECO:0000313|Proteomes:UP000185813};
RN [1] {ECO:0000313|EMBL:OKJ71373.1, ECO:0000313|Proteomes:UP000185813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0107 {ECO:0000313|EMBL:OKJ71373.1,
RC ECO:0000313|Proteomes:UP000185813};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ71373.1}.
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DR EMBL; LIVZ01000017; OKJ71373.1; -; Genomic_DNA.
DR RefSeq; WP_073944846.1; NZ_LIVZ01000017.1.
DR AlphaFoldDB; A0A1Q5JQ13; -.
DR STRING; 1703942.AMK31_34750; -.
DR OrthoDB; 5756874at2; -.
DR Proteomes; UP000185813; Unassembled WGS sequence.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR019303; vWA_TerF_C.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF10138; vWA-TerF-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000185813}.
FT DOMAIN 435..612
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..343
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 618 AA; 64466 MW; CACDF922EE3FAAC0 CRC64;
MGILTLLRNA FGRSRKPRQA EPEGATQETP ATSEAPPAQE SAPAEREAPA QQEAPARQDV
PAQQENPAPR ETPAATVPDP RPADEEHELV AAAFDNVTVP RPTQGEETAG ADTTPGPVET
PGVVETPGAE EKPKAEEKPK AEERTPVEGT AEAEEQTPVE GTAEAEEQTS VEGTAEAEEQ
TSDEKSPQAE ETAEAEKAPE PVETPKAEEQ TPVAEAPVAT EAPEAEEAPK AEQEPEPQPQ
PEASANPEPT AEAIAHEPEA LAEPEAPAEP EPTPAPEATP EPEATPEPEA TPEPEATPEP
EATPEPEATP EPEAPAEPEP TPAPDVAAEP EPTPAPKATA EPAPAATPEP AAADGEPAPQ
GPPAPDDESV TGGAGGNTTA EGEAEAEPEP ATADTKPTPA LPLTRLKSRA PALTTAYKAA
GTALKKADLT GTRAKLYLVL DRSASMRPYY KDGSAQALAE QTLALAAHVD PEATVHVTFF
STELDGTGEL TLSDHENKID ELHAALGRMG RTSYHVAVED VLAHHDKTAG PDTPALVIFQ
TDGAPDAKTP ATQALTAAAS SHPHIHFAFV AFGEHDNKAF DYLRKLKSDN ASFFHAGPAP
RELTDAELYE GVLAGWRP
//
