ID A0A1Q5KBS7_9ACTN Unreviewed; 1032 AA.
AC A0A1Q5KBS7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=OmpR/PhoB-type domain-containing protein {ECO:0000259|PROSITE:PS51755};
GN ORFNames=AMK32_29670 {ECO:0000313|EMBL:OKJ79026.1};
OS Streptomyces sp. CB01883.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703943 {ECO:0000313|EMBL:OKJ79026.1, ECO:0000313|Proteomes:UP000186398};
RN [1] {ECO:0000313|EMBL:OKJ79026.1, ECO:0000313|Proteomes:UP000186398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01883 {ECO:0000313|EMBL:OKJ79026.1,
RC ECO:0000313|Proteomes:UP000186398};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ79026.1}.
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DR EMBL; LIWA01000007; OKJ79026.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5KBS7; -.
DR OrthoDB; 3860705at2; -.
DR Proteomes; UP000186398; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000186398};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..67
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..67
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 219..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1032 AA; 108253 MW; FF2CE629CBE76F6F CRC64;
MLAVLLLRSG RAASMAELID GVWGDEPPYS AAAMMRTYAW RLRRSLDESP TQPQVLVSVG
DGYRLALDPG DVDAVRAEQL AGQAAGHRAA GRPAEAAARI GQALALWHGE PLAGVPGPHA
EQQRGRLEEV RLTLLEEHFD LLIGEGSPLL AVPELGALVS AHPLRESFHA LYIRALQRAG
RQADALAAYH RLRTQLAETL GVEPSRELRT LYQRLLADDS SSAPAGEGEA ETPGRASGFS
AAGSGRRSAA RTPDGGEGTS AGRGGAVSPG VVGQAAALST TGLPDDAGED AQGSPAPAGA
ATATSSAAAG GIFVGSPPVP AQLPAGTVDF TGRSPALDRL TRALATDHGD APPVVVITGM
GGVGKSALAV RAAHGVSARF PDGQLYADMR GNRHDPTDAG VVLTSFLTAL GVAAQFVPES
LDDRAGLLRS LLNGRRVLIL LDDVRDATQI SPLLPGAASC AVLITSRSRL WGLPTSARVD
LAAFEADEAV SLLERVVGPA RVAEDPAAAR ELVHSCGLLP LAVRIAASRL ASRPAWGARS
LAVRLADERR RMAELRAGDL TVASVFEMGY RQLSEAQARA FRLVAAVCDT EIGTPAASAV
LGMDEEDAEE QLEALVDLSL LDTSGPGRYR LHDLLRVYGQ QQATQEERLS ALDRLLDFLL
ATAAGAFQRV VPGDAVATTL SPTRSAGVRF ADVRAARDWA AAESEAAFSV VLVAARESQV
ADVAEPSAGP RAATRAPLLR VAVDLLIALT AFGPYVQREQ LVRAAVAVAE AAEGLADHRT
VGRARFLCGN IAVQSARLGV ARQHLRMAET HCRENGDAPI LRQILNDLGL VALLQHDHED
AVDRLDEAVR LARELGQRSG ALVTTVNAAL ARLRCGRVEE ARRACESALA ELRAAADHQG
VAYALSVLGL CMHELGRYDE AVARYTECLS VCRAMELHGR EAQAHYRLAD TLRALGRPAE
AVAAAGQAVA RCADGRAERD HGHALVALGR ALADLGRNAE AAARLGEAAA VFTRLELPDA
LHATALREEL PV
//
