ID   A0A1Q5KJW5_9ACTN        Unreviewed;       879 AA.
AC   A0A1Q5KJW5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=PAS domain-containing protein {ECO:0000259|PROSITE:PS50112};
GN   ORFNames=AMK32_20415 {ECO:0000313|EMBL:OKJ81769.1};
OS   Streptomyces sp. CB01883.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1703943 {ECO:0000313|EMBL:OKJ81769.1, ECO:0000313|Proteomes:UP000186398};
RN   [1] {ECO:0000313|EMBL:OKJ81769.1, ECO:0000313|Proteomes:UP000186398}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01883 {ECO:0000313|EMBL:OKJ81769.1,
RC   ECO:0000313|Proteomes:UP000186398};
RX   PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA   Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA   Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA   Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT   "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL   MBio 7:e02104-e02116(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKJ81769.1}.
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DR   EMBL; LIWA01000004; OKJ81769.1; -; Genomic_DNA.
DR   RefSeq; WP_073894677.1; NZ_LIWA01000004.1.
DR   AlphaFoldDB; A0A1Q5KJW5; -.
DR   OrthoDB; 118142at2; -.
DR   Proteomes; UP000186398; Unassembled WGS sequence.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186398}.
FT   DOMAIN          309..354
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          422..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   879 AA;  93979 MW;  8D0FD65492472DA9 CRC64;
     MSGPAPSEAP SRRFPPRPES VASARRFVRS ALSGTASDVA ETAELLAGEL VTNAVLHART
     EVEVRVDRTA DRVHVAVADR RPDRGPVPHS WLPYAGTGRG LKLLEELSAI HGVRIGDNGK
     TVWFELWPDK PVPPSSPWDA VPSPGRTVTV TLIDLPYALH AAAQQHRESL LRELALLSFG
     PAAHDLPGDL ARQELLTALD TSNLISACTT AAVQEAPDSS TLCLRSAFPA DAGPAVAALR
     LTLDLADSAA QQGALLTLPA LPQVRSFCGW LFDQIVGQLS GGPPTAWTLF PNAPSASSTE
     LAPWDAADVE ASNVPTIAAD DGNRIIAVNA AAAHLLGWQP DDLVGRRLTV LIPEHLRDRH
     AAAFGSLLLT GQPRILGRSI PLPALHRDGR LIPIRLRIQT QEALDGRTVF VAQLGARTAP
     AAPPGGDHTG HHAIRPQPGP SHPPAVRTRA RPAGNPCTDD ATLNRLSLLV DATSALTSTL
     DLTEGLHRVC RVLTRQLAQW CVVELLGEHE RVERVCVVHR TPEALKPGVR LGALPPMSEE
     TGGPLPRVLR GAGPLRLADV SSSGRLGSPL DESQEELFRQ LGARTAIIAP LRARREVLGA
     LTLVRGRDDP PFTDEDLPLV TDLVRGIALG VDNARLHEHT RRTSERMQRA LLPHLPDVDH
     LELVARYAPS GADAQIGGDW FDAFVLPKGD TALVIGDVTG HDLQSAVAMS QLRNLLRGIA
     VDRQEPPAEV VHRFDLACHT LYPHATATCV YALVKGPEGG PWELRHSSAG HPPPLLTTEQ
     GDTRYLDAGA GPLIGLDPDL PRVTADDPLP PRSTLLMFTD GLIERRGESF GDAMTRLRQH
     TAALARAPLD VFCDELVLGL GTDTTDDIAL LALRTPPPG
//