ID A0A1Q5KT35_9ACTN Unreviewed; 409 AA.
AC A0A1Q5KT35;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=FAD-dependent oxidoreductase {ECO:0000313|EMBL:OKJ84764.1};
GN ORFNames=AMK32_12335 {ECO:0000313|EMBL:OKJ84764.1};
OS Streptomyces sp. CB01883.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703943 {ECO:0000313|EMBL:OKJ84764.1, ECO:0000313|Proteomes:UP000186398};
RN [1] {ECO:0000313|EMBL:OKJ84764.1, ECO:0000313|Proteomes:UP000186398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01883 {ECO:0000313|EMBL:OKJ84764.1,
RC ECO:0000313|Proteomes:UP000186398};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ84764.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIWA01000002; OKJ84764.1; -; Genomic_DNA.
DR RefSeq; WP_073891312.1; NZ_LIWA01000002.1.
DR AlphaFoldDB; A0A1Q5KT35; -.
DR OrthoDB; 9806257at2; -.
DR Proteomes; UP000186398; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR13847:SF293; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC; 1.
DR Pfam; PF01266; DAO; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186398}.
FT DOMAIN 8..359
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT REGION 385..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 41990 MW; 43FA61E2696C38C9 CRC64;
MTKRLTCDVV VVGAGMVGAA CALYAARAGL DVRVVDRGAV AGGTTGAGEG NLLVSDKEPG
PELELALLSA GLWTELAEEL GRAIEYEPKG GLVVASTPDA LSALAAFAAG QRAAGVTAEP
VAPDELLTLE PHLAPGLAGG VLYPQDAQVM PALAAAHLLR ASGAAVHTGH TVTDVLRAAD
GPVRGVRTDR GDIHASAVVN AAGTWAADLA SLAGVRLPVL PRRGFVLVTE PLPRMVRHKV
YAADYVADVA SDSAALRASP VVEGTAAGPV LIGATRERVG FDRSLSLPAV RALAAGAIGL
FPFLARVHAQ RTYAGFRPYL PDHLPAIGPD PRAPGLFHAC GHEGAGIGLA PGTGQLIAHA
LTGGVTGQDI APFRPERFED ARFEDDGYED DAFKDDAFKD EFDDGGEAR
//
