ID A0A1Q5KT79_9ACTN Unreviewed; 406 AA.
AC A0A1Q5KT79;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Dipeptidyl aminopeptidase {ECO:0000313|EMBL:OKJ84804.1};
GN ORFNames=AMK32_12555 {ECO:0000313|EMBL:OKJ84804.1};
OS Streptomyces sp. CB01883.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703943 {ECO:0000313|EMBL:OKJ84804.1, ECO:0000313|Proteomes:UP000186398};
RN [1] {ECO:0000313|EMBL:OKJ84804.1, ECO:0000313|Proteomes:UP000186398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01883 {ECO:0000313|EMBL:OKJ84804.1,
RC ECO:0000313|Proteomes:UP000186398};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. FUS2 hydrolase
CC family. {ECO:0000256|ARBA:ARBA00038115}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ84804.1}.
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DR EMBL; LIWA01000002; OKJ84804.1; -; Genomic_DNA.
DR RefSeq; WP_073891385.1; NZ_LIWA01000002.1.
DR AlphaFoldDB; A0A1Q5KT79; -.
DR OrthoDB; 9765647at2; -.
DR Proteomes; UP000186398; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1440.110; acylaminoacyl peptidase; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR22946:SF12; CONIDIAL PIGMENT BIOSYNTHESIS PROTEIN AYG1 (AFU_ORTHOLOGUE AFUA_2G17550); 1.
DR PANTHER; PTHR22946; UNCHARACTERIZED; 1.
DR Pfam; PF12697; Abhydrolase_6; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:OKJ84804.1};
KW Hydrolase {ECO:0000313|EMBL:OKJ84804.1};
KW Protease {ECO:0000313|EMBL:OKJ84804.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186398}.
FT DOMAIN 156..382
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF12697"
SQ SEQUENCE 406 AA; 45090 MW; 6CBB445CEE07034B CRC64;
MKQLLFPNNI QFWYETLRSM SHIAYGGADF GEVVSTGERI VEGDYDSWYV EWLATADRVS
GEAEKALAAG HRVSARDGFL RASNYYRSAE FFLHGQPCDP RHDHAYDRSV ACFRAAAALF
TPVIEPVEIP YEDTTLPGYL YRVDDSGTPR PTLIMHNGFD GTAEELHFFG AMAGVERGYN
VLAFDGPGMP GPRHHEGLVF RPDWENVITP VVDFTETLPE VDDSRVALLG LSMGGILAPR
AAAFEHRLAA LIAVDGLYDL GQTSVRNIPG TREEAERLLR AQAAPELDAA LEQIMTRDPI
ARWAINHGMY VMGVDTPRAF NASYLDYTLQ DGTAERIQCP TLVCDAEEDM FFKGQPEQLY
DHLTCPRTLM TFTAEEGAGA HCHPGAMRLS IARIYDWLDD TLAATV
//
