ID A0A1Q5KTZ6_9ACTN Unreviewed; 873 AA.
AC A0A1Q5KTZ6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:OKJ85091.1};
GN ORFNames=AMK32_10650 {ECO:0000313|EMBL:OKJ85091.1};
OS Streptomyces sp. CB01883.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703943 {ECO:0000313|EMBL:OKJ85091.1, ECO:0000313|Proteomes:UP000186398};
RN [1] {ECO:0000313|EMBL:OKJ85091.1, ECO:0000313|Proteomes:UP000186398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01883 {ECO:0000313|EMBL:OKJ85091.1,
RC ECO:0000313|Proteomes:UP000186398};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ85091.1}.
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DR EMBL; LIWA01000002; OKJ85091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5KTZ6; -.
DR Proteomes; UP000186398; Unassembled WGS sequence.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OKJ85091.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186398};
KW Transferase {ECO:0000313|EMBL:OKJ85091.1}.
FT DOMAIN 340..508
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 526..746
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|SMART:SM00331"
SQ SEQUENCE 873 AA; 93610 MW; 507F24A87E299766 CRC64;
MRAAVTGRSV AGQVFVLQVV IVLLLVVAAV VAQVLQVRHD SDVEAANRSL AVAETFANAP
GTAAALRAPD PTAVLQPKAE ATREATGVDF VVVMNTDGIR YTHPKPDRIG KKFVGDIGPA
LAGGTVVEHV RGTIGPLVQV VVPVKDAQGK VVGLVSSGIT TAHVGGAADE QLPLLLAAAA
AAMALATGGT ALVSRRLLRQ THGLGPYEMT RMYEHHDAVL HAVREGVLIV GGDGRLLLAN
DEAHRLLDLP HDAERRSVLE LGLDEETAAL LASGRVVTDE VRLVKDRLLA INQRPTDLRG
GPAGSVTTLR DSTELRAVAG RAEVARERLN MLYEAGVGIG TSLDVARTAE ELAELAVPRF
ADFATVDLFD AVLKGEEPRP GTALRRTACA GLREDAPLYP VGERIRFVAT SPQARSLTTG
QSLVAARLRE APGWRAQDLE RTDQVLGYGI HSLITVPLRA GSLVLGVANF WRSEKPQPFD
SEELALAEEL VARAAISIDN ARRYTREHSM AVTLQRSLLP RSLPEQGALD IAYRYLPAQS
GVGGDWFDVL PLSGARVALV VGDVVGHGLH AAATMGRLRT AVHNFSSLDL PPDELLGLLD
ELVARIDLDE TPEEDAAVVT GATCLYAVYD PVSRRCTMAR AGHPPPALVR PDGSVEFPEI
PAGPPLGLGG LPFETAELEL AEDSRLVLYT DGLVEDRERD IDEGLELLGD ALRRTRGATP
EETCRTVLDR LPNRPSDDVA LIVARTRVLD ADRVAEWQVP SEPAAVSEVR ASVTRRLADW
GLEELAFTTE LILSELVTNA IRYGRAPIGV RLLRDRALIC EVSDRSTTSP HLRYAASTDE
GGRGLFLVAQ LADRWGTRYT PEGKIIWAEQ PLP
//
