ID A0A1Q5KUW3_9ACTN Unreviewed; 744 AA.
AC A0A1Q5KUW3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Glycogen debranching protein {ECO:0000313|EMBL:OKJ85385.1};
GN ORFNames=AMK31_14900 {ECO:0000313|EMBL:OKJ85385.1};
OS Streptomyces sp. TSRI0107.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703942 {ECO:0000313|EMBL:OKJ85385.1, ECO:0000313|Proteomes:UP000185813};
RN [1] {ECO:0000313|EMBL:OKJ85385.1, ECO:0000313|Proteomes:UP000185813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0107 {ECO:0000313|EMBL:OKJ85385.1,
RC ECO:0000313|Proteomes:UP000185813};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ85385.1}.
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DR EMBL; LIVZ01000005; OKJ85385.1; -; Genomic_DNA.
DR RefSeq; WP_073941029.1; NZ_LIVZ01000005.1.
DR AlphaFoldDB; A0A1Q5KUW3; -.
DR STRING; 1703942.AMK31_14900; -.
DR Proteomes; UP000185813; Unassembled WGS sequence.
DR GO; GO:0004133; F:glycogen debranching enzyme activity; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005980; P:glycogen catabolic process; IEA:InterPro.
DR CDD; cd11326; AmyAc_Glg_debranch; 1.
DR CDD; cd02856; E_set_GDE_Isoamylase_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR044505; GlgX_Isoamylase_N_E_set.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR004193; Glyco_hydro_13_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR011837; Glycogen_debranch_GlgX.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR NCBIfam; TIGR02100; glgX_debranch; 1.
DR PANTHER; PTHR43002; GLYCOGEN DEBRANCHING ENZYME; 1.
DR PANTHER; PTHR43002:SF1; ISOAMYLASE 1, CHLOROPLASTIC; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF02922; CBM_48; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000185813}.
FT DOMAIN 199..610
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 82718 MW; 8C21E83070042F2C CRC64;
MSSAAEQETR VGEGRPAAGV NGAAREAPAT TPVWPGAPMP LGARFRVGPD GVAGTNFALW
AGGAEAVELC LFDDDGGERR LRLTELTHEI WHGFVPGVMP GRRYGYRVHG RWDPWTGGRW
NPAKLLLDPY ARAVDGEFAL PPEVYGHVRD WPQQQVADTV RDDRDSAPYV PKGVVVHDDD
DWADDRRPKT PWADSVIYEL HVKGFTRLHP DIPEDLRGTY AGLAHPAAIE HLTRLGVTAV
ELLPVHQFAH EDHLLKRGLR NYWGYNSIGY FAPHAAYAAS GTRGQQVGEF KRMVRALHAA
GIEVILDVVY NHTAEAGELG PTLSLKGIDN RGYYRLQPDA RRYADYTGCG NTLHVVQPHV
LRLITDSLRY WVTEMGVDGF RFDLAAALAR SMHDVDMLSP FLAVIAQDPV LRRVKLIAEP
WDVGSGGYQV GAFPPLWTEW NDRYRNAVRD FWRHALPDVR EMGYRLSGSS DLYAWGGRRP
YASVNFITAH DGFTLRDLVS YERKHNEANG EGNRDGSNDN RAWNCGAEGD TDDERVRALR
RRQLRNLLTT LLLSTGVPML VAGDELGRTQ GGNNNAYCQD NEISWLDWSL LEDPGWRALT
ELTARLIALR HQHPVLRRRA FFSGRAHSAD GLRDLAWFTA RGTEMTERDW YAPAATLGMY
LSGRDIPGRD ERGAPILDDS FLAVLHAGER PVSFVLPGPP WAERYEVVVD TSEEEQATAP
GVTHPAGAAI TVPGRSVLLL KVVG
//
