ID A0A1Q5L9X3_9ACTN Unreviewed; 459 AA.
AC A0A1Q5L9X3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Hydrolase {ECO:0000313|EMBL:OKJ91672.1};
GN ORFNames=AMK33_35165 {ECO:0000313|EMBL:OKJ91672.1};
OS Streptomyces sp. CB02400.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703944 {ECO:0000313|EMBL:OKJ91672.1, ECO:0000313|Proteomes:UP000185993};
RN [1] {ECO:0000313|EMBL:OKJ91672.1, ECO:0000313|Proteomes:UP000185993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02400 {ECO:0000313|EMBL:OKJ91672.1,
RC ECO:0000313|Proteomes:UP000185993};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ91672.1}.
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DR EMBL; LIWB01000023; OKJ91672.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5L9X3; -.
DR Proteomes; UP000185993; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050313; F:sulfur dioxygenase activity; IEA:InterPro.
DR GO; GO:0004792; F:thiosulfate sulfurtransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR CDD; cd07724; POD-like_MBL-fold; 1.
DR CDD; cd00158; RHOD; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 2.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR044528; POD-like_MBL-fold.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR001307; Thiosulphate_STrfase_CS.
DR PANTHER; PTHR43084; PERSULFIDE DIOXYGENASE ETHE1; 1.
DR PANTHER; PTHR43084:SF1; PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF00581; Rhodanese; 2.
DR SMART; SM00849; Lactamase_B; 1.
DR SMART; SM00450; RHOD; 2.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 2.
DR PROSITE; PS00380; RHODANESE_1; 1.
DR PROSITE; PS50206; RHODANESE_3; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:OKJ91672.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000185993}.
FT DOMAIN 266..357
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 372..451
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 459 AA; 48062 MW; CA369A05249BF1CF CRC64;
MGFADEHLIP LVDEGLGNSA YLLDLGDGRA LAMDAGRDLR ALREAAEQRG LTVAYAADTH
LHADFLSGAV QLGHDTGATV LASAAGRRAF AHRALAGGDE VDLGGLTLRA LSTPGHTDEH
LSFLLLDGGR ELGVFTGGSL IVNSAARTDL LGPERTEELA RAQYRSLRLL TELPDETAVW
PTHGAGSFCS APPGTGRTST IGAQRQTNPL LAAPDENAFV DRLIASLGTY PTYFDRLGET
NRRGPAVLTA QPVLPVLSAR QVQALMADGG YVVDVRPAAD YAAGHIPGSL SIPLRDQFAT
WLGWLLPDTA PLAFVTSEGQ DLSEIVWQAY KIGYERLAGR LTGGMDAWLA DGNPQATTAF
LTADRAVGRP YVDVRQQAEF AAGHVPGAVH LELGSLPAAA GDAPTAPVVA CGHGERAMTA
ASLLERAGHT DIAVLDGGPD DYTAAHGRQL AQGTEGHRS
//
