ID A0A1Q5LUH2_9ACTN Unreviewed; 346 AA.
AC A0A1Q5LUH2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=ATP/GTP-binding protein {ECO:0000313|EMBL:OKK05623.1};
GN ORFNames=AMK33_22425 {ECO:0000313|EMBL:OKK05623.1};
OS Streptomyces sp. CB02400.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703944 {ECO:0000313|EMBL:OKK05623.1, ECO:0000313|Proteomes:UP000185993};
RN [1] {ECO:0000313|EMBL:OKK05623.1, ECO:0000313|Proteomes:UP000185993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02400 {ECO:0000313|EMBL:OKK05623.1,
RC ECO:0000313|Proteomes:UP000185993};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|ARBA:ARBA00005582}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK05623.1}.
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DR EMBL; LIWB01000009; OKK05623.1; -; Genomic_DNA.
DR RefSeq; WP_073934789.1; NZ_LIWB01000009.1.
DR AlphaFoldDB; A0A1Q5LUH2; -.
DR Proteomes; UP000185993; Unassembled WGS sequence.
DR CDD; cd02883; Nudix_Hydrolase; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR020476; Nudix_hydrolase.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43046; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR PANTHER; PTHR43046:SF12; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PRINTS; PR00502; NUDIXFAMILY.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000185993}.
FT DOMAIN 199..332
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 346 AA; 37689 MW; DA239E9F162BB148 CRC64;
MIVWVNGTFG AGKTTTAREL IELIPNSTLF DPEVIGGALE RLLPPKRLAE VGDFQDLPIW
RRLVIDTAAA MLAELGGTLV VPMTLLRQEY RDEIFGGLAA RRIPVRHVLL APAETILRER
IAAREVPADL PDGEIRVRQW SYDHIEPYKA ALAAWLTADA YPVDSGTLSP YETALRIAEA
VGSGEAPACD IVQTPEPTAE TVAAGVLLFD EQDRVLLVDP TYKPGWEFPG GVVERGEAPA
RAGMREVAEE TGIRLDDVPA LLVVDWEPPA PPGFGGLRLL FDGGRLDSAT AGRLLLPGPE
LRGWRFASEA EAADLLPPVR YERLRRALRA RERGKAMYLE AGVPVG
//
