ID A0A1Q5LZZ9_9ACTN Unreviewed; 421 AA.
AC A0A1Q5LZZ9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Biotin carboxylase {ECO:0000313|EMBL:OKK07502.1};
GN ORFNames=AMK09_36095 {ECO:0000313|EMBL:OKK07502.1};
OS Streptomyces sp. CB02488.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703920 {ECO:0000313|EMBL:OKK07502.1, ECO:0000313|Proteomes:UP000186200};
RN [1] {ECO:0000313|EMBL:OKK07502.1, ECO:0000313|Proteomes:UP000186200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02488 {ECO:0000313|EMBL:OKK07502.1,
RC ECO:0000313|Proteomes:UP000186200};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK07502.1}.
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DR EMBL; LIVO01000022; OKK07502.1; -; Genomic_DNA.
DR RefSeq; WP_073739247.1; NZ_LIVO01000022.1.
DR AlphaFoldDB; A0A1Q5LZZ9; -.
DR STRING; 1703920.AMK09_36095; -.
DR OrthoDB; 24041at2; -.
DR Proteomes; UP000186200; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR041472; BL00235/CARNS1_N.
DR InterPro; IPR040570; LAL_C2.
DR PANTHER; PTHR43585:SF2; ATP-GRASP ENZYME FSQD; 1.
DR PANTHER; PTHR43585; FUMIPYRROLE BIOSYNTHESIS PROTEIN C; 1.
DR Pfam; PF13535; ATP-grasp_4; 1.
DR Pfam; PF18130; ATPgrasp_N; 1.
DR Pfam; PF18603; LAL_C2; 1.
DR SMART; SM01209; GARS_A; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000186200}.
FT DOMAIN 116..312
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 421 AA; 43688 MW; 1241C0C124C02958 CRC64;
MSERLLLLVE SNTTGTGRLF ARRAAELGVV PVLLCADPGR YPYAAEDRLR TVTVDTSDED
ALWAAVRTLE DGATVAGVLT SSEYYVPAAA ALAYRLGLPG PSAEAVRACR DKAEQRRALT
GAGVGSADFA AVSEVAGALA AARGIGLPVV VKPVQGSGSL GVRLCTDLDE VAEHAGTLLA
ATVNERGITA PGRILVEEYL TGPEFSVEVF GTEAVVTVAK HVGPLPAFVE TGHDVPAALT
GEQEIALRET AVRAVRALGL GWGAAHVELR LTGTRTAQVI EVNPRLAGGM IPELVRRACG
TDLVRAQVLA ALGAAPELER TGHARASIRF LTCDRDGILA PSAALHEAVD RARTVPGTVE
ALLYRAPGEP VGPAEDFRGR VGHVIAVADR SGRAAEAAGR AVALLGEAVT YADLHTEEAY
A
//
