ID A0A1Q5MBU8_9ACTN Unreviewed; 370 AA.
AC A0A1Q5MBU8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Polyprenyl synthetase {ECO:0000313|EMBL:OKK11676.1};
GN ORFNames=AMK33_09710 {ECO:0000313|EMBL:OKK11676.1};
OS Streptomyces sp. CB02400.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703944 {ECO:0000313|EMBL:OKK11676.1, ECO:0000313|Proteomes:UP000185993};
RN [1] {ECO:0000313|EMBL:OKK11676.1, ECO:0000313|Proteomes:UP000185993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02400 {ECO:0000313|EMBL:OKK11676.1,
RC ECO:0000313|Proteomes:UP000185993};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK11676.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIWB01000003; OKK11676.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5MBU8; -.
DR Proteomes; UP000185993; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR NCBIfam; NF041169; f2_encap_cargo4; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000185993};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 38280 MW; D575CFDDAB4DE541 CRC64;
MTESITEPKT GLTAESTAEM PAVPEQRPGD GHEATMLLER ARAAVDPVLR AALGSLPGPM
RRVALYHFGW EQADGTPAGG GSGKAIRPAL VLAAASALGG PVARASAVRA AAAVELIHNF
TLLHDDVMDR DTTRRHRPTA WTVFGDADAI LAGDALQALA LRLLAVDPHP AASAAAARLA
DCVVELCAGQ HADTAMEQRG PDEVTLAETL AMAEAKTGAL LGCACAIGAL YADAQDADVV
ALDGFGREAG LAFQLIDDVI GIWGDPRRTG KPAGADLAAR KKSLPVVAAL TSGTPEAAEL
AAVYATPHHK EDDLEEIALA VERAGGRDWA QTQAADRMAR AMQEVARAVP DPEAAGGLLA
LAEFVTRRTT
//
