ID A0A1Q5MII6_9ACTN Unreviewed; 823 AA.
AC A0A1Q5MII6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=PAS sensor protein {ECO:0000313|EMBL:OKK13945.1};
GN ORFNames=AMK33_03860 {ECO:0000313|EMBL:OKK13945.1};
OS Streptomyces sp. CB02400.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703944 {ECO:0000313|EMBL:OKK13945.1, ECO:0000313|Proteomes:UP000185993};
RN [1] {ECO:0000313|EMBL:OKK13945.1, ECO:0000313|Proteomes:UP000185993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02400 {ECO:0000313|EMBL:OKK13945.1,
RC ECO:0000313|Proteomes:UP000185993};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK13945.1}.
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DR EMBL; LIWB01000001; OKK13945.1; -; Genomic_DNA.
DR RefSeq; WP_073931243.1; NZ_LIWB01000001.1.
DR AlphaFoldDB; A0A1Q5MII6; -.
DR Proteomes; UP000185993; Unassembled WGS sequence.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000185993}.
FT DOMAIN 33..66
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 823 AA; 89062 MW; 37E1C70AEE992456 CRC64;
MDRGTERDAP PERRAGDGAA AERGGAGRVP LAVVVVDRDG LVSHWSRGAR RLFSLAKEDA
LGRPAVDLLP VTGALPEEPG EPGEEEPYGA YAAYDGLGPG LGASLGGGLS YPAAGRARLA
AAGAGRVDVL WWAYPLVGPG RERLLVLAAD ADGLLRTDGA GTFERIAPGF ALHTDFPGSE
DLARRLPEIL PSMSVGDSAR IVAQVLELGY PVLEFSQNDR VPVTPDWGVP RRIERRERRE
RAARALAAGE PVPEELRDEG EDLEYAAVRE RLEFLNEVSS RIGTSLDLSR TIVEVSKAVV
PRFTDVAGTY LREQVVAGEG FDEGVPDTTT MWHRVALEHT DEPGRWDDVV PVGEAMPFPA
HTPFFQCMTT GEPVLVPRVS EEMGHAIASQ FEKRDIRPLI TGRSMLVVPL KARHAVLGFM
ILLRHPERQV FNDMDRVTGA ELAARAGLVL DNARMYTYQE NVAETLQDSM LPHIPPRMAG
CDIATRYLPG TLLGRIGGDW FDAVKLPGAR TAFVVGDVMG HGLNSAAMMG QLRTAVQTMA
ALDLPPTQLL RNLDDLAQRL GDTYLATCLY AVYDPIASEL RLANAGHIPP VLVRAADGRS
ELLDLPTGAP IGVGGVPFET VRVPVEPGDR LVMCTDGLVE VRGEDIGVGL ATLCESAAHP
AASMDDACDT IIRKLNTHGG RKDDVALLMA RLGGIEPDDV AEWRLAPDPS EVGRARAVVR
EQLHDWGLPK LVDSTELMVS ELVTNAVLHS HARPVALRLV RGDTLLCEVE DDDHELPTLL
DARPADEFGR GLRVVSTLAR QWGTSRTTTG KSVWFELTLP RRR
//
