ID A0A1Q5MUM7_9ACTN Unreviewed; 250 AA.
AC A0A1Q5MUM7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=AMK09_19325 {ECO:0000313|EMBL:OKK17872.1};
OS Streptomyces sp. CB02488.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703920 {ECO:0000313|EMBL:OKK17872.1, ECO:0000313|Proteomes:UP000186200};
RN [1] {ECO:0000313|EMBL:OKK17872.1, ECO:0000313|Proteomes:UP000186200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02488 {ECO:0000313|EMBL:OKK17872.1,
RC ECO:0000313|Proteomes:UP000186200};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK17872.1}.
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DR EMBL; LIVO01000007; OKK17872.1; -; Genomic_DNA.
DR RefSeq; WP_073736102.1; NZ_LIVO01000007.1.
DR AlphaFoldDB; A0A1Q5MUM7; -.
DR STRING; 1703920.AMK09_19325; -.
DR OrthoDB; 3654490at2; -.
DR Proteomes; UP000186200; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR Pfam; PF13676; TIR_2; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186200}.
FT DOMAIN 1..144
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 195..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 250 AA; 27704 MW; F0DBDED0C4BAC509 CRC64;
MTDVFINYRT GDGETTATLI DQELSRRFGR ERIFRASKSI APGRLYPDEL LHGLRRSSVL
LAVIGPDWTN FRVKLRDPQD WVRREIAEAF ACELPVVPVL DGRKTDRLNK KDLPDELARL
ADLQSIAFST HDTEAGLKRI GDVVADMVPG LRDLDLDDAE PLVPDSVVNS IRDVSGTAVQ
SRDFTGDVGT VIKGAGGPVH TGQGDIYQNS RHESGGRHFS GSGMTYVEGE LHGGVQHRFD
EPDRREDDVR
//
