ID A0A1Q5MW30_9ACTN Unreviewed; 724 AA.
AC A0A1Q5MW30;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Murein biosynthesis protein MurJ {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMK16_18075 {ECO:0000313|EMBL:OKK18251.1};
OS Streptomyces sp. CB00455.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703927 {ECO:0000313|EMBL:OKK18251.1, ECO:0000313|Proteomes:UP000185643};
RN [1] {ECO:0000313|EMBL:OKK18251.1, ECO:0000313|Proteomes:UP000185643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB00455 {ECO:0000313|EMBL:OKK18251.1,
RC ECO:0000313|Proteomes:UP000185643};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK18251.1}.
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DR EMBL; LIVQ01000004; OKK18251.1; -; Genomic_DNA.
DR RefSeq; WP_073916888.1; NZ_LIVQ01000004.1.
DR AlphaFoldDB; A0A1Q5MW30; -.
DR STRING; 1703927.AMK16_18075; -.
DR OrthoDB; 9786339at2; -.
DR Proteomes; UP000185643; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd13123; MATE_MurJ_like; 1.
DR InterPro; IPR004268; MurJ.
DR NCBIfam; TIGR01695; murJ_mviN; 1.
DR PANTHER; PTHR43549:SF1; LIPID II FLIPPASE MURJ-RELATED; 1.
DR PANTHER; PTHR43549; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR Pfam; PF03023; MurJ; 1.
DR PRINTS; PR01806; VIRFACTRMVIN.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185643};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 192..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..703
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..117
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 75836 MW; 4604D0A8EE07767A CRC64;
MNAPYDGDRA QGTGGPAPAQ GTAPGTPVPG QVPAPAPAPD HDPYVQDAYG YDPYRSQDLS
AQDPVAEVLY DRASHPPPPP GTYQEPGPLY AAPASPSYAP DPRVWAQTPP PEPDGPSRHL
PYGDHATTTE FVGVDSLVTK AADEQPEPDA FAHLYRDQEA APRIPAEDAP VAAPAPARPA
GRASSLLKSS ALMAAGTIVS RITGFLRTLV IAGAIGVGTF NDTYQIANTL PTMIYVLVGG
GALNAVFIPQ LVRAMKNDDD GGQAYANRLL SLVVVLLAAV TTICVLAAPV FITMMSPKIA
SDPQQMDVAV AFARYCLPTM FFMGVHVVLG QILNARGRFG AMMWTPVLNN IVVIATFGAF
IWAFGGFTTS GVNATTVTPE GVRLLGLGTL LGLTVQALAM LPYLRDAGFK PRLRFDWKGH
GLGKAARLAK WTFFFVLANQ VGLVVVTQLA TWAGSVAEKQ GHPGTGITAY NYALLLWQMP
QAIITVSVMT AVLPRISRSA HDGDAAAVRD DISYGLRTSA VAIVPCAFAF LALGVPMATL
LYAGSGAGAQ NIGYVLMAFG LGLIPYSVQY VVLRGFYAYE DTRTPFYNTV IVAAVNAAVS
TASFFVLPAR WAVVGMAAAY GLGYTVGVGV AWRRLRTRLG GDLDGAHVMR TYARLTGACV
PAAAVAGAVA YGITQWLGGG VGGSAAALVA GGIALAGVFL IAAKRMRIEE LNSMVGMVRG
RLGR
//
