ID A0A1Q5MWX0_9ACTN Unreviewed; 348 AA.
AC A0A1Q5MWX0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Histidinol phosphatase {ECO:0000313|EMBL:OKK18767.1};
GN ORFNames=AMK09_17745 {ECO:0000313|EMBL:OKK18767.1};
OS Streptomyces sp. CB02488.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703920 {ECO:0000313|EMBL:OKK18767.1, ECO:0000313|Proteomes:UP000186200};
RN [1] {ECO:0000313|EMBL:OKK18767.1, ECO:0000313|Proteomes:UP000186200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02488 {ECO:0000313|EMBL:OKK18767.1,
RC ECO:0000313|Proteomes:UP000186200};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK18767.1}.
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DR EMBL; LIVO01000006; OKK18767.1; -; Genomic_DNA.
DR RefSeq; WP_073735807.1; NZ_LIVO01000006.1.
DR AlphaFoldDB; A0A1Q5MWX0; -.
DR STRING; 1703920.AMK09_17745; -.
DR OrthoDB; 9808747at2; -.
DR Proteomes; UP000186200; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07436; PHP_PolX; 1.
DR Gene3D; 1.10.150.110; DNA polymerase beta, N-terminal domain-like; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR010996; DNA_pol_b-like_N.
DR InterPro; IPR027421; DNA_pol_lamdba_lyase_dom_sf.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR047967; PolX_PHP.
DR InterPro; IPR017078; UCP036978_PHPhdr.
DR PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR Pfam; PF14716; HHH_8; 1.
DR Pfam; PF02811; PHP; 1.
DR PIRSF; PIRSF036978; UCP036978_PHPhdr; 1.
DR SMART; SM00481; POLIIIAc; 1.
DR SUPFAM; SSF47802; DNA polymerase beta, N-terminal domain-like; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186200}.
FT DOMAIN 103..182
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 348 AA; 37878 MW; 3BD53A33DE78BBFA CRC64;
MDPVRALERI AFLLERGGAG TYRVQAFRTA ARTVAAMAEG EAVQRVTNGS LERVKGIGPR
TAQVIREAVA GELPGYLEGL ETEAQEHGPL AEGGERLLAL LRGDCHLHSD WSDGGSPIEE
MGRTAAELGH DWAVLTDHSP RLTVANGLSP ERLREQLDVV AELNERWAPF RLLTGIECDI
NLDGTLDQED ELLDRLDLVV VSVHSKLRMD PGPMTQRLLA AVRHPRANVL GHCTGRLVTG
RGRPESRFDA DEVFAACAEA GTAVEINCRP ERLDPPRRLL RQAVDAGTLF AIDTDAHAPG
QLDWQAYGCA RAEECGVPAE RVVTTWTADE LLDWTREGRA PAGARADS
//
