ID A0A1Q5N0S9_9ACTN Unreviewed; 1000 AA.
AC A0A1Q5N0S9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Helicase {ECO:0000313|EMBL:OKK20083.1};
GN ORFNames=AMK09_15845 {ECO:0000313|EMBL:OKK20083.1};
OS Streptomyces sp. CB02488.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703920 {ECO:0000313|EMBL:OKK20083.1, ECO:0000313|Proteomes:UP000186200};
RN [1] {ECO:0000313|EMBL:OKK20083.1, ECO:0000313|Proteomes:UP000186200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02488 {ECO:0000313|EMBL:OKK20083.1,
RC ECO:0000313|Proteomes:UP000186200};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK20083.1}.
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DR EMBL; LIVO01000005; OKK20083.1; -; Genomic_DNA.
DR RefSeq; WP_073735435.1; NZ_LIVO01000005.1.
DR AlphaFoldDB; A0A1Q5N0S9; -.
DR STRING; 1703920.AMK09_15845; -.
DR OrthoDB; 9760715at2; -.
DR Proteomes; UP000186200; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR022138; Helicase_SWF/SNF-rel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799:SF1020; BTAF (TBP-ASSOCIATED FACTOR) HOMOLOG; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF12419; DUF3670; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:OKK20083.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186200}.
FT DOMAIN 546..699
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 832..991
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 254..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1000 AA; 106574 MW; A29CBA9394795AEC CRC64;
MSVVSPPQDA AVGRLLRCAA VFLPAPLPRE GRVAFWDPEG APLPGLVTAS GAGLGSGADD
RVSELTVVRR HGDQGAVRRQ TVPALVLPLA DAVPLLARAR HQQSAHPATR CWGAAALHAL
HLVAGGRMLP GLTPDDHDAW RAGPRAAEDV AHLRAVAAAM PPEGYAVPFP DRTPLQVPEP
EPLIASFLDA VADTLPRTPA AAFAMGAPFA ATEAQHLPGA REWAVAVAAG LDAGVRVSLR
LDLSAYELFD TTYSDGAPDS DGAPDADGVT NSDGVAEFDG PPDAADGTAG PGRPDTAARH
AAAAVTQVHS LADPTYVVDA AALWNGGAGE PFGPRARIDA VLALRRAARV WAPLERLLDQ
PVPDVLALTE DELYELLSDA GARLSAAGVS VHWPRELARS LTAAAVVRPA PGTATDGTAF
FDAEQLFAFN WQLSLGDQQL TEAEMDVLAE AHRPVVRLRD QWVVVDPALV RKARKRELGL
LDPVDALAVA LTGSAEVDGE QVDAVPVGAL AALRSRIVDD DTTIAPPPGL DATLRDYQLR
GLAWLDRMTA LGLGGCLADD MGLGKTITLI ALHLHRAHPA PTLVICPASL LGNWHREINR
FAPGVPVRRF HGTDRSLAEP DGGFVLTTYG TMRSSAAELA AHSWGLVVAD EAQHVKNPHS
STAKALRTIP SPARVALTGT PVENNLSELW ALLDWTTPGL LGPLKAFRAR HARIVENTGT
AAGIGNDEAV ERLSRLVRPF LLRRKKSDPG IAPELPPKTE TDHPVFLTRE QATLYEATVR
ETMAYIEASE GIARRGLIMK LLASLKQICN HPAQYLKEEP TRLTGRSGKL ALLDELLDTI
LAEDGSVLVF TQYVTMARLL SAHLTSRAIP SQLLHGGTPV AERERMVDRF QSGEVPVFLL
SLKAAGTGLN LTRAAHVIHY DRWWNPAVEE QATDRAYRIG QTQPVQVHRL IAEGTVEDRI
GEMLLAKRAL ADAVLGAGET ALTELSDRDL ADLVSLRRPS
//
