ID A0A1Q5N2Z3_9ACTN Unreviewed; 450 AA.
AC A0A1Q5N2Z3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMK16_10265 {ECO:0000313|EMBL:OKK20797.1};
OS Streptomyces sp. CB00455.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703927 {ECO:0000313|EMBL:OKK20797.1, ECO:0000313|Proteomes:UP000185643};
RN [1] {ECO:0000313|EMBL:OKK20797.1, ECO:0000313|Proteomes:UP000185643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB00455 {ECO:0000313|EMBL:OKK20797.1,
RC ECO:0000313|Proteomes:UP000185643};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK20797.1}.
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DR EMBL; LIVQ01000002; OKK20797.1; -; Genomic_DNA.
DR RefSeq; WP_073912257.1; NZ_LIVQ01000002.1.
DR AlphaFoldDB; A0A1Q5N2Z3; -.
DR STRING; 1703927.AMK16_10265; -.
DR OrthoDB; 9784366at2; -.
DR Proteomes; UP000185643; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185643};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 84..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 29..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 47707 MW; D185730C6B31D687 CRC64;
MTKRAGWLGR LGNRLNRMEA LLHERRAEVE AETGGELPGR AASGREPAPA ASGAEGRSVL
APVRIERPDP VSVVPWGMRV AAEVSWRLLL LAGMLWVLMK VISEVRLVVL AFAAALLVTA
LLQPFVVRLR RLGIPRGLAT AGTAILGFVV IGLVGWFVVW QVMENLDDLS DRVRDGINEL
KLWALDSPFH VTEKQINDIA KNLSETIGTN TEEITSAGLQ GVTVLVEVLT GILLAMFSTL
FLLYDGKRIW TWVLGLVPAA ARPGMAGAGP RAWRTLTAYV RGTVLVALID AIFIGLGIYF
LKVPMAVPLA VFIFLFAFIP LVGAVVSGAL AVVVALVTQG VFSALMVLLV VLAVQQIEGH
VLQPFILGRA VRVHPLAVVL SVAAGGMIAG IGGAVVAVPL VAVTNTVVGY LRTYSRAQLH
HGSPPAGPGP HGATALDIAL PETAGDEQRA
//
