ID A0A1Q5N4V8_9ACTN Unreviewed; 358 AA.
AC A0A1Q5N4V8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=YihY/virulence factor BrkB family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMK09_13425 {ECO:0000313|EMBL:OKK21470.1};
OS Streptomyces sp. CB02488.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703920 {ECO:0000313|EMBL:OKK21470.1, ECO:0000313|Proteomes:UP000186200};
RN [1] {ECO:0000313|EMBL:OKK21470.1, ECO:0000313|Proteomes:UP000186200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02488 {ECO:0000313|EMBL:OKK21470.1,
RC ECO:0000313|Proteomes:UP000186200};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKK21470.1}.
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DR EMBL; LIVO01000004; OKK21470.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5N4V8; -.
DR STRING; 1703920.AMK09_13425; -.
DR OrthoDB; 3209118at2; -.
DR Proteomes; UP000186200; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR017039; Virul_fac_BrkB.
DR PANTHER; PTHR30213:SF0; RIBONUCLEASE-LIKE PROTEIN YFKH-RELATED; 1.
DR PANTHER; PTHR30213; UNCHARACTERIZED; 1.
DR Pfam; PF03631; Virul_fac_BrkB; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186200};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 306..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..358
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 358 AA; 38947 MW; F13997C22E4C9C94 CRC64;
MAWQLLKDTV NSCMEYRILG LAAEAAFFTL LSLPPLLLGL IGLLGYVDEW TSTTTVASIE
NNILSAAQTV LSQRGVNDFA KPLLADVTTG ARPDVISIGF AIALWSGSRA VNVFIDTITV
MYGLDGQRGI VKTRMLAFSL YVVALLLGAI VLPLLVVGPD RVVEYIPWGT ELISVMYWPL
VILLSIAFLT TLYHVSVPVR SPWIEDTPGA LMALAIWVLG SFLLRIYLTS TVEGPTIYGS
LAAPIAVLLW IGVSAFAVLV GAAVNAAIDR VWPSVATAAA RAANDRVRAV QAAEFVARAQ
AESWDGDMDD EYGDEGDSPY MPSEFPERWS RFLPPDDVKS RLQPGREKEP DKPYRPSE
//
