ID   A0A1Q5PPB3_9ACTO        Unreviewed;       603 AA.
AC   A0A1Q5PPB3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Peptidoglycan glycosyltransferase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BM477_04460 {ECO:0000313|EMBL:OKL49377.1};
OS   Boudabousia marimammalium.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Boudabousia.
OX   NCBI_TaxID=156892 {ECO:0000313|EMBL:OKL49377.1, ECO:0000313|Proteomes:UP000186465};
RN   [1] {ECO:0000313|Proteomes:UP000186465}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15383 {ECO:0000313|Proteomes:UP000186465};
RA   Meng X.;
RT   "Actinomyces gypaetusis sp. nov. isolated from Gypaetus barbatus in Qinghai
RT   Tibet Plateau China.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKL49377.1}.
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DR   EMBL; MPDM01000004; OKL49377.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q5PPB3; -.
DR   STRING; 156892.BM477_04460; -.
DR   Proteomes; UP000186465; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186465};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          39..226
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          278..579
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   603 AA;  64452 MW;  2C88C19ADD5E3334 CRC64;
     MLLAALVIFL VVVLFRVQVV LGPEYAAQGV KGRSVSYTLD APRGTIYDAA GNVLASSSTR
     YDIIADPTNI AQYVHYEKGQ DNKYHIVGVG PVEAARQLAP ILDMDEAILG GMLSQPPHSE
     VEGKAAQAQV LNKTAERNPY KSQYKVIATK VTPEVRREII DLNITGISTH VRSERLYPKG
     ATAANILGFM AADPKDNSNT VGIAGIELIM EDTLKSTPGR GSVEVAGRTG AVIPGGVREE
     TPAQAGTSIH LSLNSDLTAF SQEVADQTQA KHGAEWVVVV VEEVKTGRIL AIGDSGVKAF
     KDVKDFTNVQ FGSHAVKDTY EPGSTGKLIT MAAALEKGVV QPLTPFSCPG KITMPNGQEF
     RDSHEHPTER LSAAGIIAQS SNTCIVQVGD KVKDQERYDL MRAFGWGEKS GIQLPSESGG
     ILESPEKWDG RQRYTTMFGQ GVATTPLQVT NMLATIGNGG VRNQSRILDG YTKPDGQYEK
     VPLSSPQRVI SSDSAQILLN MMQGVVSEDG TAKRVDVPGY NVAGKTGTTQ IFGRKGYVGS
     FAGLIPAEDP VAAILVVTYR PKTTAYGSVV AVPAFNQVAQ RTMQVLGVPP STAKPELYPV
     RVK
//