ID   A0A1Q5PPB6_9ACTO        Unreviewed;       471 AA.
AC   A0A1Q5PPB6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Sodium:alanine symporter family protein {ECO:0000313|EMBL:OKL49394.1};
GN   ORFNames=BM477_05175 {ECO:0000313|EMBL:OKL49394.1};
OS   Boudabousia marimammalium.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Boudabousia.
OX   NCBI_TaxID=156892 {ECO:0000313|EMBL:OKL49394.1, ECO:0000313|Proteomes:UP000186465};
RN   [1] {ECO:0000313|Proteomes:UP000186465}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15383 {ECO:0000313|Proteomes:UP000186465};
RA   Meng X.;
RT   "Actinomyces gypaetusis sp. nov. isolated from Gypaetus barbatus in Qinghai
RT   Tibet Plateau China.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKL49394.1}.
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DR   EMBL; MPDM01000004; OKL49394.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q5PPB6; -.
DR   STRING; 156892.BM477_05175; -.
DR   OrthoDB; 9806926at2; -.
DR   Proteomes; UP000186465; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186465};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        64..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        94..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        176..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        209..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        236..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        341..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        384..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   471 AA;  49626 MW;  C95E41CB918D59E9 CRC64;
     MSQLADQFLV IGDWLTIHVT VIILTLAGVV FTISTRGVQF RHFGRMVKAV LGSRQGAKGG
     ISSFQAFTIS LAARVGIGNV FGVAYALMAG GPGAIFWMWI VALLGMSTAF FEATTAQIFK
     VRTSDGAFVG GPAYYLSRGL KKRWLGIVFA LITVITCAFS ITMVQSNAIS ATMEGYGVAT
     PALTATALVV FTGVVVIGGI RRVARVTEIL APLMATIYVI LAFVIVLINI TEVPRLFGMI
     FASAFSPEPL VGGLGGGILA ALINGVKRGL FSNEAGQGTA PNAAATATAA HPVQQGLIQS
     LGVFVDTIIV CTATAFVILL AGKEVWIDPS SNPGTLTTSS VAASLGSWTV VPMALMIFVL
     AYSSIIAAYV YSEVNLRFFT DSSVATWTVR VISVVSVALG ALFPLDIVWN TVDIAMALMT
     AFNLVGLLLL VRWGMGALKD YESQIKAGKE PQFVATDNKF LPGPLEGDAW T
//