ID   A0A1Q5QAS1_9EURO        Unreviewed;      2052 AA.
AC   A0A1Q5QAS1;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Negative regulator of mitosis {ECO:0000313|EMBL:OKL63047.1};
GN   ORFNames=UA08_02029 {ECO:0000313|EMBL:OKL63047.1};
OS   Talaromyces atroroseus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Trachyspermi.
OX   NCBI_TaxID=1441469 {ECO:0000313|EMBL:OKL63047.1, ECO:0000313|Proteomes:UP000214365};
RN   [1] {ECO:0000313|EMBL:OKL63047.1, ECO:0000313|Proteomes:UP000214365}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 11181 {ECO:0000313|EMBL:OKL63047.1,
RC   ECO:0000313|Proteomes:UP000214365};
RA   Rasmussen K.B., Rasmussen S., Petersen B., Sicheritz-Ponten T.,
RA   Mortensen U.H., Thrane U.;
RT   "Talaromyces atroroseus IBT 11181 draft genome.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKL63047.1}.
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DR   EMBL; LFMY01000002; OKL63047.1; -; Genomic_DNA.
DR   RefSeq; XP_020123168.1; XM_020261759.1.
DR   STRING; 1441469.A0A1Q5QAS1; -.
DR   GeneID; 31001784; -.
DR   OrthoDB; 180933at2759; -.
DR   Proteomes; UP000214365; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR049255; Apc1_N.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF12859; ANAPC1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000214365}.
FT   DOMAIN          30..801
FT                   /note="Anaphase-promoting complex subunit 1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12859"
FT   REGION          201..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          330..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        205..219
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..369
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2052 AA;  227118 MW;  9C897FEAA6EA3179 CRC64;
     MASVRSLGLH DPPALPFLVH EALLPIEPSD EDYKWCTQGP ESDDDIIYTK NCAVWSRGGV
     VKRVFKIEIE KEEIHHVVLT SFPSVCAEAQ SDGTADIHSA SRLQTDSQGD TTKVIVAPID
     RGSTKGRMYP YRDPSKALVV VLKTQAHIFF LAGNTHVVPL PFEVDSVFAS PRGLIFQRRL
     PDETPTPFPE APPNSFMSYQ THSEHRQSHI FRSSRGREKR ASPILGLAQP SRLPQKRSDD
     LDMPRTFSLS DPHSEMGHVV ANQSTHATHH TQDSWAYDSL DPAEEIVYVS AVNELLGDSP
     SVKESPLVLV VTINAVTRLY TIWTAKFRGE TSGQESRKRK KPLPSGARSK RRSSHYGMTT
     GTTTPVVRPS GLRESIGASR SLPGASFSQS FQAEEPLEQA DFASQMGQEF EDIGVPSKTS
     RRVSSLLART ELGASQDRMT FSDLATGNQG NTANHGSLRQ SIGAYSTRAS FGGRNLRNSF
     AGNASVYSTT SSFLDAPVDR LLEELNNGGD FEGFGSMDLT GPMSGLHKEM MLRKVESFSS
     GLSSGSFSFT ELKQSRSKPK AFTLRPTESV HQETSSSSPI ALCLLDETSR CLVVVNLSIQ
     NVSLSSRDRA ASRKHGKSEN SNGKTTIVQA IGIHHAPNVM DVCKVVDGEV SRILTLKSTM
     DGKGELSLQS PWGPSTKIEL PPKLLLHQPQ RYSAVQNRAQ DAGMKRVIGD QNLNLTAFGH
     SSAHGQVDII DSEKRRHRIE IQLQPKNPLV KKVLAVCRFV LRDAIRAADG LYTAWWEVLR
     WLISGGVDEN DLEWTALVVV LFTMAVGFID SPQSRTPAAK KQRRRGNILR SSSGSYIDQE
     SWESMTEKLA GSSGVTAPWM MSSSWTWVSG LRDDHNGKHF LTEQQAQNGQ SKNSYLLRCV
     SLARDFFDSP QGEAASGSEG YLPTALCQSQ TTRRSALCSI LVGLHLLREE QKLSICDSES
     SYHEIGMLAP ILAQIGGWVG WKSWTWKEDS YYGTEMATVS GWAFEDSQIS GLELPSEPFA
     PPSIFGHLQS SVLSQTANNF ATLLDILTNV DRASDKIALR NEVMSLTPRT LALNGFMSEV
     HEMSSPADKV KLLLRWGLTT SVIESLPEGV NAPLFELIVR CQIEPPTSCT AALIGLIDRD
     DLYMSMKTET ISLPSSRPQL GASHLSVRDV HHIGASTLDF ELSNSFEASV EADRIFITRL
     MFREDRRFQE ASRLLNQSKA PVAQCFPEPE WSDSDLLEAQ KEIVQLVTLR TLSVPAGRAM
     FMFSGRSPLL TEKLPIPSFS LQCLMKPSNV TISADRSAFN EEKVCWAFFH NGAATGLAIS
     KASKGIDTSW ILFNKPQELT NRHAGFLLAL GLNGHLKNLA KWVAFKYLTP KHTMTSIGLL
     LGLSVSYLGT MDTLITRLLS VHVTRMLPQG AAELNLSPLT QTAGIMGIGL LYCDSQHRRM
     SEVLLSEIES VEQEEGTISP ETLRDEGYRL AAGFSLGLIN LGKGKDLRGL RDMQVVERLL
     TLAIGTKNVD LVHVLDRATP GATVALAIIF MKTNDELLAR KVDIPDTTVQ FDYVRPDLFL
     LRTLARHLIM WDSIKPSSEW LLSKIPKTYR KRHRLSTIRH LSSDDMPFFN IIAGLCFAIG
     LRYAGSAHSE ARDLLIRYLD QFRRIVRLPA LHYDSKLARN SVRHCQDIVA ISAAAVMAGT
     GDLTLFRRLR SLHGRVDADT TYGSHMAAHM AIGLLFLGGG CYTLGTSNLA VASMLFAFYP
     LFPTSVLDNK CHLQAFRHLW VLAAEPRCLI ARDVDSRRPI SIPVSLKMKD GTTREATAPC
     LLPNLEEIAS VKAHGRDHWP LVLDFDRNDE LRGKFRRGDQ SIYLRRNTTY DPSGNSVFAS
     TLLGLSEAQD ILTSSVIGSW KKPIPNAAAL LVMQGQKNKT TRHDVWDWIF SLRPLQNLDV
     TDRSAVLPPS VFQFRLRYAA SSQGSVVTPS WLRLSSVDTR LVLESTVNEA VEEAFGNGGM
     TRQAFDVIKD RLWQLRLLFD WINRQAETER QNKGDSAGLQ KRAAAGGGWL NREVIEQAQW
     RIWGIRVGDQ LS
//