ID   A0A1Q5R3Z8_9BRAD        Unreviewed;       594 AA.
AC   A0A1Q5R3Z8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=AC629_40390 {ECO:0000313|EMBL:OKO70440.1};
OS   Bradyrhizobium sp. NAS80.1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=1680159 {ECO:0000313|EMBL:OKO70440.1, ECO:0000313|Proteomes:UP000186592};
RN   [1] {ECO:0000313|EMBL:OKO70440.1, ECO:0000313|Proteomes:UP000186592}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAS80.1 {ECO:0000313|EMBL:OKO70440.1,
RC   ECO:0000313|Proteomes:UP000186592};
RA   Granada C., Sant'Anna F.H., Passaglia L.;
RT   "Genome of Bradyrhizobium sp. NAS80.1.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKO70440.1}.
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DR   EMBL; LGHL01000281; OKO70440.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q5R3Z8; -.
DR   Proteomes; UP000186592; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          12..127
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REPEAT          425..458
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   594 AA;  65108 MW;  B913E5CC9EFDC56F CRC64;
     MTDNRVERRL AAILAADVAG YSRLMGADEE GVLAHLKTAR KSLVDPTIAA HRGRIVKTSG
     DGMLVEFASA VDAARCAIEV QRGMVEQNST VPRARRIEFR VGIHVGDIIV DDNDIFGDGV
     NIAARLEGIA EPGGICLSDD AQRQIRGKVD IAFEDMGPQN LKNIVEPMRT WRLQMNVDVS
     ATASAEWSTD TTQSSLPDKP SIAVLPFQNM SGDTEQEYFA DGLSEDIITE LSRISSMSVI
     ARNSAFVYKS RPVDVKQAGR ELGVRYILEG SVRRSNQRVR VTAQLVETTT GGHLWAEKYD
     RSLANIFEIQ DEITRSVVAS TQTQVVLREG ALAERSERPD FRTWDLAKQG LKNIYALTQE
     SIAEARKVAT ELTRIDASFA KGHQLLAAAT YHLALMGFCD DRGAMLGDAL QSARNAIRLD
     DRDEYSHWIL GGVLGQGLGQ HDKAVAAYRR ALELNPNFSL AFGSLGTVLA LAGEPDESVR
     NSEICISANP RDPSIFFRFS GLALAYFVAE DYPRSREWAA RSVARKREWW QGHALLASSC
     VLLGKGDEAG AAVHDWLAAF PSARISNLPP IPFKKATDLK RFHDALRSAG LPEG
//