ID A0A1Q5SV93_9EURO Unreviewed; 1309 AA.
AC A0A1Q5SV93;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE SubName: Full=Protein ste16 {ECO:0000313|EMBL:OKO91903.1};
GN ORFNames=PENSUB_12976 {ECO:0000313|EMBL:OKO91903.1};
OS Penicillium subrubescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1316194 {ECO:0000313|EMBL:OKO91903.1, ECO:0000313|Proteomes:UP000186955};
RN [1] {ECO:0000313|EMBL:OKO91903.1, ECO:0000313|Proteomes:UP000186955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 132785 {ECO:0000313|EMBL:OKO91903.1,
RC ECO:0000313|Proteomes:UP000186955};
RA De Vries R.P., Peng M., Dilokpimol A., Hilden K., Makela M.R.,
RA Grigoriev I., Riley R., Granchi Z.;
RT "Genome sequence of the ascomycete fungus Penicillium subrubescens.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKO91903.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MNBE01000744; OKO91903.1; -; Genomic_DNA.
DR STRING; 1316194.A0A1Q5SV93; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000186955; Unassembled WGS sequence.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186955}.
FT DOMAIN 113..182
FT /note="REM-1"
FT /evidence="ECO:0000259|SMART:SM00742"
FT DOMAIN 252..615
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 694..918
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 1101..1172
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 138..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..228
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1309 AA; 145999 MW; CF14A2EFBD402145 CRC64;
MASGHNSAFS ASTQHRALGD GRSSFSQDGG SGDGSWNDGL SKIGRTGRSG SGGSATTGTR
GASSLAPSFG GPGSFSAELK SMTSRSVTPR PDGTYGRRAS RSIGEDDLPT TEERQAVIRD
KIAKEMKIKT GTENMLEALL AKPPKQTKEQ RLRVESELSS SNRKLAELHH ELEEELLRAQ
APGTTPPRSR LSSLFRTSPM RSPSRNPLNI GPESLEDDQD DEEDGDMESP TYVLSETLQA
LEIEGMSPDF YVERANNLVE LFKRHPTLKY DLAWPVFGLR VQVMLLSDSK EEVAAGYRLT
RYAIADRKSL QTIRALHTDE LVILSLVKES KASIEREQAL KFVRAFLDVK DGVKEISRAI
VRTIVSVAEH HDDRLRNISI MTLAEILVKD PELVASAGGF AALHDALAEG TFGASESLIS
SFLHVTDTPR SRKYLQGSEL EAVLAPFTDS LADTLRNGRL KSAARAISAM LKTWPGLVIL
ARHEFKPLHS LLESLHYPDT QARDLILELL FDALRIKPPS WSSSFLAGRR LTTYGRVSNL
RSDTDSKSNR TYHDSGTNKF DLTAHFSTLI LAALIAAGLP QALSDLIEDE TDLSLRRKAT
LLLTEVLKMA HHSLPAAISA NLQVLAHLLP PAIQFDMEKH DVSTSTIFQI ESINRTLARS
GGYSGGAGRY NLDPDLSVSL LPGEQAKDKL SPSMDEQTFR NAILETHVLN SVNYMKWKWD
LIHRLVEGPL TNPKRMDEAI KGSKFMKRLL GFYRPFKYRF AMVPNTKPNQ RYVRTGCALM
RTLVMSAEGI KYLAENKFLR QVAECLAQLD RMSGLTSASP LFSREQMVNT LSGGYFAMLG
TLSADASGLL MMERWHMLNM FYHIIELQDR NDLIQTLLGN MDYSRASHLR VMLSKALTIG
SKDIRIFATK LLRKYAVGDV SLSPQMAIGN AEWVVKLLVT QLYDPDVTVC QIAVKILEEA
CNQRDYLEFV VKCRPSLDHL GEIGAPLLLR FLSTSVGYHY LDGLDYITQE MDDWFLGRND
SYVGLVEAAL SRAYVDQPRR NSFAPEDLVD LQDVGVVPPH FYRELARTAE GCKLLEQSGH
FNEFAWTIRD FRLEEEDTEV LLKVKGCLWA VGNVGSMELG APFLEPEIVQ RIVAIALRAG
VLTMRGTAFF VLGLISRSKH GLRVLRDLGW DSAIDQNGES LGFCLPTDFR QLFLISFPGR
HPDSRRTPQH KLKEATTDPD PVNQKILKLM VDMGNTVLSK RSAGDLHSMK SKQPERFHQV
HLFRKALCIL ESHHYRLPAR RFAIDLFDKS VMRRIVLEED SESDSDSST
//
