ID A0A1Q5T6K6_9EURO Unreviewed; 771 AA.
AC A0A1Q5T6K6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 03-MAY-2023, entry version 21.
DE RecName: Full=DNA polymerase epsilon subunit B {ECO:0000256|ARBA:ARBA00016011};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN ORFNames=PENSUB_10882 {ECO:0000313|EMBL:OKO95861.1};
OS Penicillium subrubescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1316194 {ECO:0000313|EMBL:OKO95861.1, ECO:0000313|Proteomes:UP000186955};
RN [1] {ECO:0000313|EMBL:OKO95861.1, ECO:0000313|Proteomes:UP000186955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 132785 {ECO:0000313|EMBL:OKO95861.1,
RC ECO:0000313|Proteomes:UP000186955};
RA De Vries R.P., Peng M., Dilokpimol A., Hilden K., Makela M.R.,
RA Grigoriev I., Riley R., Granchi Z.;
RT "Genome sequence of the ascomycete fungus Penicillium subrubescens.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKO95861.1}.
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DR EMBL; MNBE01000701; OKO95861.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5T6K6; -.
DR STRING; 1316194.A0A1Q5T6K6; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000186955; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186955}.
FT DOMAIN 452..729
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 83488 MW; FD7F7A0BFE05311D CRC64;
MDPTSTPRHP DRFRMGAGAE DPIPSSSPAF ATPARPFRMP RGHAPPTKTS ILPILLPPAT
LRPVAFRTFT RKHNLTISSS ALQTLAVFIG KNCGSGWREE GLAEKALDEV AKIWKRAGGG
VIVEEGKGAS LKAILQTLES SMSGGRVVAG KGNSQDGKSS GLGVDAGRMD TSNDHSQGSL
TMRAGDVDED ESKLSCHSRH WLKVVDAFDL PRLTYNVDKK YFEALKSKPT LFPPPSHKTA
LFRDRYNLVY QRLLRNESFQ SSLGVAGMPS LQRSSSNLGM QQSYKLTPIA NLLGRSGTSH
LLLGLLSISP TGDLSLVDLT GTVALDLSHA RMIPEDGAWF APGMIVLVDG IYEEEEMVQG
SMLGGNHGVG GAIGGHFVGV SICGPPCERR DISLGTGSRQ ASGDVSSSGG FGWVDFLGTG
SERAQGARMR RLQEKCLRGA PESTESTARL KVAILNEVNL DNMKTLDALR KVFSTYNDLA
LCERPQTFVL IGNFVQKAII NGGGRAGSIE YKEYFDSLAV VLADFPALLQ HSTFVFVPGD
NDPWASSFST GAASTIPRQP IPELFTSRIR RAFATANSEL DRTQTSEPAG EALWTSNPTR
LSWFGPVHDI AIFRDDISGR LRRTAINMHK DEEEAETTDP MQETLDEATN EAVSFAPDLD
QQNGSKSNGA SSAAASMARK LVKTILDQGT MAPFPLQLRP VLWDHSSAVQ LYPLPTALVL
ADAEAAPFCM TYEGCHVMNP GRLLPLGDGQ AVKWIEFDVL RNRGRVKEER Y
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