ID   A0A1Q5UCK2_9EURO        Unreviewed;       740 AA.
AC   A0A1Q5UCK2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OKP10193.1};
GN   ORFNames=PENSUB_4367 {ECO:0000313|EMBL:OKP10193.1};
OS   Penicillium subrubescens.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1316194 {ECO:0000313|EMBL:OKP10193.1, ECO:0000313|Proteomes:UP000186955};
RN   [1] {ECO:0000313|EMBL:OKP10193.1, ECO:0000313|Proteomes:UP000186955}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 132785 {ECO:0000313|EMBL:OKP10193.1,
RC   ECO:0000313|Proteomes:UP000186955};
RA   De Vries R.P., Peng M., Dilokpimol A., Hilden K., Makela M.R.,
RA   Grigoriev I., Riley R., Granchi Z.;
RT   "Genome sequence of the ascomycete fungus Penicillium subrubescens.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKP10193.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MNBE01000379; OKP10193.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q5UCK2; -.
DR   STRING; 1316194.A0A1Q5UCK2; -.
DR   OrthoDB; 49329at2759; -.
DR   Proteomes; UP000186955; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049456; Anoctamin_N_fung.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF77; MEMBRANE STRESS RESPONSE PROTEIN (IST2), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03330)-RELATED; 1.
DR   Pfam; PF04547; Anoctamin; 1.
DR   Pfam; PF20877; Anoctamin_N; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186955};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        182..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          19..141
FT                   /note="Anoctamin alpha-beta plait"
FT                   /evidence="ECO:0000259|Pfam:PF20877"
FT   DOMAIN          174..635
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
FT   REGION          674..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        674..694
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   740 AA;  83865 MW;  7146F2102ED9AF59 CRC64;
     MSWLAGHEKH GHDESDNLGV DWVLQYEFGD IEQAQAISEF RTLIHDLTEA GLRVQIRHGH
     GFALLVFIRV PRDHLGKMVH QSRIKDWLFG IIYTLPSGDE NTIASAETPA EEIRSIYHAV
     TWRKELGGAG ITPGFGKWKN ITASFPLHDR DACSELLSKW NRKTNLTVED LDTIRALFGE
     KVAFYFAFIH CYSLFLVAPA AMGIVGWWFL GPYSIIYGSA LMIWCIVFVE FWKIRETDLS
     VRWNVKGVGQ LKVNRSQYQW EKEVKDPISG QVTQTFPGWK QFLRQMLLLP FASVASVALG
     TLIVVTFASE VFISEVYNGP LKGYLEFVPT ILFSLSLPAI TSFLTGIATR LTDYENYRTQ
     DLYDLAQTQK TFVMHFITSF LPTILTAYVY VPFGHAIVPH LDILRRVGIN TASHKGFEVD
     TSRFQAEVIY LSMTAQVFSF AEEIVLPYVK HVLWQKWRNY RERKAGLTRQ RSFSKATDLL
     LIDSPEESSF LRRVRGEADA DEYKVEEDIL EMCVQFGYLA LFGVAWPLVP LGFLLNNWLE
     VRGDFFKLTL ECQRPPPIRA DSIGPCLLGL DFLSWMGTLS TAAIVHLYRG PMSSVRLSSL
     LLTVFIAEQV YLGIRFTAST ALQKIFSDTL RREEASRYAV RKSFLEMNQS RHGGPDSPSR
     VRQRVRFHER VNVYSSDTAS PDGSPSPTSE QPQDEVLRGS DREAGFWEAR ECDTADAGVK
     LIRALSGGKG VGEVKEVKHA
//