ID A0A1Q5UIG3_9EURO Unreviewed; 586 AA.
AC A0A1Q5UIG3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Histone deacetylase clr3 {ECO:0000313|EMBL:OKP12270.1};
GN ORFNames=PENSUB_2006 {ECO:0000313|EMBL:OKP12270.1};
OS Penicillium subrubescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1316194 {ECO:0000313|EMBL:OKP12270.1, ECO:0000313|Proteomes:UP000186955};
RN [1] {ECO:0000313|EMBL:OKP12270.1, ECO:0000313|Proteomes:UP000186955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 132785 {ECO:0000313|EMBL:OKP12270.1,
RC ECO:0000313|Proteomes:UP000186955};
RA De Vries R.P., Peng M., Dilokpimol A., Hilden K., Makela M.R.,
RA Grigoriev I., Riley R., Granchi Z.;
RT "Genome sequence of the ascomycete fungus Penicillium subrubescens.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKP12270.1}.
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DR EMBL; MNBE01000228; OKP12270.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5UIG3; -.
DR STRING; 1316194.A0A1Q5UIG3; -.
DR ESTHER; 9euro-a0a1q5uig3; Arb2_domain.
DR OrthoDB; 124800at2759; -.
DR Proteomes; UP000186955; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR019154; Arb2-like_domain.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR017321; Hist_deAcase_II_yeast.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF09757; Arb2; 2.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PIRSF; PIRSF037919; HDAC_II_yeast; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186955};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 458..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..246
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 294..373
FT /note="Arb2-like"
FT /evidence="ECO:0000259|Pfam:PF09757"
FT DOMAIN 387..569
FT /note="Arb2-like"
FT /evidence="ECO:0000259|Pfam:PF09757"
SQ SEQUENCE 586 AA; 66111 MW; A99C7EB08D185317 CRC64;
MSDEELVYLE KTRDSIYFNR LTFTSSLLSA GGAIETCLAV ARRQVKNAIA VIRPPGHHAE
HDTAMGFCLF NNVPVAARVC QNVLGDECRK IMILDWDVHH GNGVQKAFYN DPNVLYISIH
VYQSGKFYPG GDEGDWDHCG EGPGLGKNVN IPWPDQGMGD GDYMHAFQKV VMPIALEFDP
DLVIISAGFD AAAGDVLGGC FVSPSCYAQM THMLMTLANG KVAVCLEGGY NFRSISKSAL
AVTKTLMGEP PDRLSKTTPT QDAIETVGRV MNIQAQYWRC MYPKPPQHLT GADRLHDVIR
QYQAQQLYEH FKLTPLFIYR TKISKSFENQ VLASANYHER VPLIVIFHDP PELMGYPDPV
TSRLEAHNCW MVSVPSIVAN RLELIIANIC KADTIKDYIG WILSKGYAVI DVNIPKHISQ
IPATGKFEKD DENRPTVTEE LVNYLWDNYI DFHEKREVFF FGIGGAFSGV VNFLINRENM
YKRVSGIVSF VAKNPVRAVN SNTQVWLSKW YRDNSLVFVS DSHSVWKNEE RKPSKRYGKL
YRSSKSSLSE MMTESQQQVF EWLADRADEA LDETEDEVDE DLPMKG
//
