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Database: UniProt
Entry: A0A1Q5ZYL0_9SPHI
LinkDB: A0A1Q5ZYL0_9SPHI
Original site: A0A1Q5ZYL0_9SPHI 
ID   A0A1Q5ZYL0_9SPHI        Unreviewed;       790 AA.
AC   A0A1Q5ZYL0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   08-MAY-2019, entry version 13.
DE   SubName: Full=Putative 3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:OKS86828.1};
GN   ORFNames=RG47T_2285 {ECO:0000313|EMBL:OKS86828.1};
OS   Mucilaginibacter polytrichastri.
OC   Bacteria; Bacteroidetes; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Mucilaginibacter.
OX   NCBI_TaxID=1302689 {ECO:0000313|EMBL:OKS86828.1, ECO:0000313|Proteomes:UP000186720};
RN   [1] {ECO:0000313|EMBL:OKS86828.1, ECO:0000313|Proteomes:UP000186720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RG4-7 {ECO:0000313|EMBL:OKS86828.1,
RC   ECO:0000313|Proteomes:UP000186720};
RA   Li Y.;
RT   "Whole Genome Sequencing of Mucilaginibacter polytrichastri RG4-7(T)
RT   isolated from the moss sample.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OKS86828.1}.
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DR   EMBL; MPPL01000001; OKS86828.1; -; Genomic_DNA.
DR   RefSeq; WP_074489523.1; NZ_MPPL01000001.1.
DR   BioCyc; GCF_001911425:RG47T_RS11050-MONOMER; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000186720; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.1040.10; -; 2.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000186720};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186720}.
FT   DOMAIN        9    195       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      198    297       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   COILED      540    560       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   790 AA;  87200 MW;  B48B1B8CB7FE6FC0 CRC64;
     MSFKRIIKKV AVLGSGVMGS RIACHFANIG MQVLLLDIVP KDADAKSRNK LVNDALTAAL
     KSNPSPIYSK SLAKNITTGN FEDDMSKIAD CDWVIEVVVE RLDIKQIVFE QVEKFRKAGT
     LITSNTSGIP IHLMAEGRSE DFRKHFCGSH FFNPPRYLKL LEVIPTNETL PEVVDFLMHF
     GEKYLGKTTV LAKDTPAFIG NRIGVFSIMS ILHYAEKTGI TIEEVDKLTG PVIGHPKSAT
     FRTSDVVGLD TMVHVANGLS QGVPNDEAKD LFQIPEFVTK MVANNWLGSK SGQGFYKKDK
     VNGANVFSTL DLKTLEYQPS KKVKFPSLET TKTIDKLSDR IKVLFAAKDK AGDFYRAIFY
     QLFAYASNRI PEITEDLYKI DAAMNAGFGW ETGPFEKWDA LGVEATIQAM EADNLKPAQW
     VYDMVASGAT SFYKIEDGKK LYYNIPSKTY KIIPGTEEFI LLDNIRATNT IWKNSGTTIT
     DLGDGIINLE FHTKMNTIGG EVIEGINKAI TLAEQGYKGL VISNEGANFS AGANVGMIFM
     MAVEQEFDEL NMVIKAFQNT MMRIRYSSIP VIAAPHQMAL GGGCELCLHA DKVVAHAELY
     MGLVEFGVGL IPGGGGTKEF ALRLSDELQE GDIEMNNFRD RFLTIGQAKV STSAAEAFEL
     GYLKKGRDLV VVSRNRVLSE AKKQCLAMAE EGYTQPVPRK DIRVLGKSAL GLGYVGANTM
     FSGNYISEHD VKISQKLAYV MAGADLSQPT LVSEDYLLNL EREAFIQLCA ERKTLERIQS
     ILTGGKVLRN
//
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