ID A0A1Q6CEX6_9GAMM Unreviewed; 751 AA.
AC A0A1Q6CEX6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:OKY24933.1};
GN ORFNames=BI291_04210 {ECO:0000313|EMBL:OKY24933.1};
OS Thalassotalea sp. PP2-459.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Thalassotalea.
OX NCBI_TaxID=1742724 {ECO:0000313|EMBL:OKY24933.1, ECO:0000313|Proteomes:UP000186791};
RN [1] {ECO:0000313|EMBL:OKY24933.1, ECO:0000313|Proteomes:UP000186791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PP2-459 {ECO:0000313|EMBL:OKY24933.1,
RC ECO:0000313|Proteomes:UP000186791};
RA Barja J.L., Dubert J.;
RT "Draft genome of the tyrosinase inhibitors producing Thalassotalea sp. PP2-
RT 459.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKY24933.1}.
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DR EMBL; MKQD01000072; OKY24933.1; -; Genomic_DNA.
DR RefSeq; WP_074500059.1; NZ_MKQD01000072.1.
DR AlphaFoldDB; A0A1Q6CEX6; -.
DR STRING; 1742724.BI291_04210; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000186791; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:OKY24933.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:OKY24933.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186791};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..145
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
SQ SEQUENCE 751 AA; 83478 MW; E2B6FA6801D82AAC CRC64;
MLNKDLEISL NMAFRQAKES RHEFMTVEHL LLALLDNPSS IQALKACGAD MIKLRQELLD
FIAETTPVIP AEEEERETQP TLGFQRVLQR AVFHVQSSGK SEVSGSNVLV AIFSEQESQA
AYFLKKSDIN RLDIVNYISH GIAKAEGQPS NKAHEEINQQ EEEPRTVENF ATNLNEQAKV
GRIDPLIGRA SELERTLQVL GRRRKNNPLF VGEAGVGKTA IAEGLANLIV SEKVPEFLAD
TIIYSLDLGA LLAGTKYRGD FEKRFKALLK ELEQEGNAIL FVDEIHTIIG AGAASGGMMD
ASNLIKPLLS SGKLRCVGST TYQEYQNIFE KDRALARRFQ KIDIVEPSID DTTKILQGLK
EKYESHHGIR YTNKALRAAA QLSAKYINER FLPDKAIDVI DEAGAKQQLL ASSKRKKVIN
DGDIEIIVAK MARIPEKSVS SSEKDSLHTL DRNLKLVVFG QDHAIDELTS VVRLSRAGLG
QENKPVGSFL FAGPTGVGKT EVTQQLSKVL GVELLRYDMS EYMEKHAVSR LIGAPPGYVG
YEQGGLLTDA VIKHPHAVVL LDEIEKAHPD VYNILLQVMD HGTLTDNNGR KADFRNITLV
LTTNAGVAET TRQSIGFKQQ DHSFDALNEI NKIFSPEFRN RLDNIIWFNH LDDNVIHQVV
DKFIVELQAQ LDDKGVSLEL TKDAKKWLAV NGYDKAMGAR PMSRLIQEHL KKPLANELLF
GDLVQGGVAK VGVKKDKLVL SFESKKELVE H
//
