ID A0A1Q7HLJ9_9CHLR Unreviewed; 303 AA.
AC A0A1Q7HLJ9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:OLC52289.1};
GN ORFNames=AUH85_17490 {ECO:0000313|EMBL:OLC52289.1};
OS Chloroflexi bacterium 13_1_40CM_4_68_4.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1805077 {ECO:0000313|EMBL:OLC52289.1, ECO:0000313|Proteomes:UP000185706};
RN [1] {ECO:0000313|EMBL:OLC52289.1, ECO:0000313|Proteomes:UP000185706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27843720;
RA Butterfield C.N., Li Z., Andeer P.F., Spaulding S., Thomas B.C., Singh A.,
RA Hettich R.L., Suttle K.B., Probst A.J., Tringe S.G., Northen T., Pan C.,
RA Banfield J.F.;
RT "Proteogenomic analyses indicate bacterial methylotrophy and archaeal
RT heterotrophy are prevalent below the grass root zone.";
RL PeerJ 4:E2687-E2687(2016).
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLC52289.1}.
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DR EMBL; MNFM01000188; OLC52289.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q7HLJ9; -.
DR Proteomes; UP000185706; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:OLC52289.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 8..276
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 303 AA; 31957 MW; A70C4C26CF22C603 CRC64;
MIRLPGRLTV VEVGPRDGLQ SEERVLPTET KVRFIERLAD AGLSVIEATS FVSPNAVPQL
ADAAEVLRAL RRRPGVRYPV LVPNETGLER ALSAGATEIA VFGSASETYS RKNLNRSRDA
AIAMFRPVVR RAKDAGLRVR GYLSMVIADP WEGPLAPAVV VDAGRRLLEL GCDELSLGDT
TGVGTPASIE RLLRAFLDAG IVAESIGVHF HDTYGQALAN VLVALTLGIT VVDASAGGLG
GSTVIKGAHG NLATEDLLWL CRGSGIETGV ELDAVAGTSA WVARELGRPL QGRAARAVLP
RSD
//
