ID A0A1Q7MJX7_9CREN Unreviewed; 386 AA.
AC A0A1Q7MJX7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN ORFNames=AUI93_01995 {ECO:0000313|EMBL:OLD12954.1};
OS Crenarchaeota archaeon 13_1_40CM_3_52_10.
OC Archaea; Thermoproteota.
OX NCBI_TaxID=1805095 {ECO:0000313|EMBL:OLD12954.1, ECO:0000313|Proteomes:UP000186650};
RN [1] {ECO:0000313|EMBL:OLD12954.1, ECO:0000313|Proteomes:UP000186650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27843720;
RA Butterfield C.N., Li Z., Andeer P.F., Spaulding S., Thomas B.C., Singh A.,
RA Hettich R.L., Suttle K.B., Probst A.J., Tringe S.G., Northen T., Pan C.,
RA Banfield J.F.;
RT "Proteogenomic analyses indicate bacterial methylotrophy and archaeal
RT heterotrophy are prevalent below the grass root zone.";
RL PeerJ 4:E2687-E2687(2016).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family.
CC {ECO:0000256|ARBA:ARBA00006184, ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLD12954.1}.
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DR EMBL; MNGO01000020; OLD12954.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q7MJX7; -.
DR STRING; 1805095.AUI93_01995; -.
DR Proteomes; UP000186650; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763:SF26; CELL DIVISION CONTROL PROTEIN 6 HOMOLOG; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01407};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01407}.
FT DOMAIN 294..378
FT /note="Cdc6 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01074"
FT BINDING 53..57
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 200
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 212
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 386 AA; 43937 MW; DF1743D25DE7F3B1 CRC64;
MFKDEGPLSL EWLPTRLPHR ENQLRFLAEL FRSVIDKPGT TSPKVLITGD IGTGKTVLTQ
RFGTDIQRTA KTLKLNLAYI HVNCREYRGS LFMILKRVLQ TFTPQFPQRG FSSEELLHIL
LDQLEDKKLH IILTLDEADS LIKAEGSTSL YNLTRIQEEL PGRPVRLSLI IILRDLKNLE
DLDRSTQSTL QRNVIRLDHY TTPQLENILR ERAELAFKEA TVPEEVLNFV ADMATLGGDA
RYAIELLWRG GKYADTEGAR EVKPDHIRAA ANSVYPVLRT EYSQHLNLHE KLILLALARV
LERNNATYAT MGDVEIAYRM ACEEHKETYR AHTQVWKYVQ NLNATGILST QLSTTGFRGK
TTLLGISSAP ASTIRRWLES TLSIRA
//
