ID A0A1Q7T0J9_9BACT Unreviewed; 526 AA.
AC A0A1Q7T0J9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=PQQ-dependent dehydrogenase, methanol/ethanol family {ECO:0008006|Google:ProtNLM};
GN ORFNames=AUF67_05760 {ECO:0000313|EMBL:OLD82022.1};
OS Acidobacteria bacterium 13_1_20CM_58_21.
OC Bacteria; Acidobacteriota.
OX NCBI_TaxID=1803438 {ECO:0000313|EMBL:OLD82022.1, ECO:0000313|Proteomes:UP000186215};
RN [1] {ECO:0000313|EMBL:OLD82022.1, ECO:0000313|Proteomes:UP000186215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27843720;
RA Butterfield C.N., Li Z., Andeer P.F., Spaulding S., Thomas B.C., Singh A.,
RA Hettich R.L., Suttle K.B., Probst A.J., Tringe S.G., Northen T., Pan C.,
RA Banfield J.F.;
RT "Proteogenomic analyses indicate bacterial methylotrophy and archaeal
RT heterotrophy are prevalent below the grass root zone.";
RL PeerJ 4:E2687-E2687(2016).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- COFACTOR:
CC Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC Evidence={ECO:0000256|ARBA:ARBA00001931};
CC -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008156}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLD82022.1}.
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DR EMBL; MNIJ01000081; OLD82022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q7T0J9; -.
DR Proteomes; UP000186215; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 1.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR017512; PQQ_MeOH/EtOH_DH.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR NCBIfam; TIGR03075; PQQ_enz_alc_DH; 1.
DR PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR PANTHER; PTHR32303:SF20; QUINOPROTEIN ETHANOL DEHYDROGENASE; 1.
DR Pfam; PF13360; PQQ_2; 3.
DR SMART; SM00564; PQQ; 6.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..526
FT /note="PQQ-dependent dehydrogenase, methanol/ethanol
FT family"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012999885"
FT REGION 349..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 56890 MW; 98A1470340035247 CRC64;
MQLASMALLG LGGLASSARA QVTPQRLLDS GKEPQNWLMY SGDYAGHRFS ALDQINAPNA
AMLVPKWVYQ TMAGGKFETT PLVVDGILYG TGQDNRAFAL DARSGRPIWQ YQRALAADIR
PCCGRVNRGM AILGDKVFLG TLDAHIIALD AKTGSVVWDA TSADYRNGYS ITLAPLVIKN
LVLIGVSGGE YGIRGFIDAY DAATGERKWR FYTIPGPGEA GHETWEGESW KIGGAPAWIT
GTYDPATNTT FWTTGNPSPS NRGEGRAGDN LYSNSLLALD PDTGKLKWYF QFSKHDEHDY
DATQVPVMVD QGDQHVIVQA NRNGFFYLID RTNGKVVFAN PFAKETWSDS KDASGAPIAR
KDASPTLEGN RVCPGAAGAT NWMSPTYDPQ TRLFYVTARE QCDVFSTAPQ PYEAGHAFYG
SAYFPNDDAE PFTGALRAID PHTGKLKWEW KHLSPTWSGV LSTAGGLVFT GDAEGNFIAL
EAASGKALWH FQCGASVYSS PMSFAIDGKQ YVAVAAGSAL FAFSLP
//
