ID   A0A1Q7VTB4_9ACTN        Unreviewed;       958 AA.
AC   A0A1Q7VTB4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Peptidase S53 domain-containing protein {ECO:0000259|PROSITE:PS51695};
GN   ORFNames=AUG49_21300 {ECO:0000313|EMBL:OLE21721.1};
OS   Catenulispora sp. 13_1_20CM_3_70_7.
OC   Bacteria; Actinomycetota; Actinomycetes; Catenulisporales;
OC   Catenulisporaceae; Catenulispora.
OX   NCBI_TaxID=1805055 {ECO:0000313|EMBL:OLE21721.1, ECO:0000313|Proteomes:UP000186605};
RN   [1] {ECO:0000313|EMBL:OLE21721.1, ECO:0000313|Proteomes:UP000186605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27843720;
RA   Butterfield C.N., Li Z., Andeer P.F., Spaulding S., Thomas B.C., Singh A.,
RA   Hettich R.L., Suttle K.B., Probst A.J., Tringe S.G., Northen T., Pan C.,
RA   Banfield J.F.;
RT   "Proteogenomic analyses indicate bacterial methylotrophy and archaeal
RT   heterotrophy are prevalent below the grass root zone.";
RL   PeerJ 4:E2687-E2687(2016).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OLE21721.1}.
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DR   EMBL; MNJN01000329; OLE21721.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q7VTB4; -.
DR   Proteomes; UP000186605; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd04056; Peptidases_S53; 1.
DR   CDD; cd11377; Pro-peptidase_S53; 1.
DR   Gene3D; 3.40.50.12090; -; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR007253; Cell_wall-bd_2.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015366; S53_propep.
DR   InterPro; IPR030400; Sedolisin_dom.
DR   PANTHER; PTHR14218:SF42; PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR14218; PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2; 1.
DR   Pfam; PF04122; CW_binding_2; 3.
DR   Pfam; PF09286; Pro-kuma_activ; 1.
DR   SMART; SM00944; Pro-kuma_activ; 1.
DR   SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51695; SEDOLISIN; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          229..641
FT                   /note="Peptidase S53"
FT                   /evidence="ECO:0000259|PROSITE:PS51695"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   958 AA;  97172 MW;  DE9E92EAE07DBED4 CRC64;
     MVAAATQAMP AQADDTQHSK HDNKMLNNAH PGWATADKDR GAVPASQRIT TRVFLTGQDP
     DGLAAAARAV TDPDSPGYQQ YLTADQIKQR FGATPAQIAA VQDWLKSAGL SISAVSGDWI
     DAEGDAGAVQ KAFGTQIKNY QRPDGSVGYA ASSAAVIPGS VAGLVAGVSG LSQATTRAHT
     DSAQGSGITS DGDPSPGCGS TTTTYWGQYS ATGWPAGSNG STIPVLPCPY SPQQLRQAYG
     LTHTGKGARI AVVDWYASKT MYSDAQQWSA DHKIQQFRDG QYTEWKNEGA WNHTSGADAC
     GSAAAEESLD VEMAHGLAPD ADIVYVGANS CTDQDLMAAE QLIVDKHLAD VVSNSWGEII
     HGTDGDADPA VMAGYDRIFQ KGALEGISFT FSSGDCGDDD PANKAGGAVN CNGNSARKQT
     EWPVSSQWVT AVGGTTLATN SSGYAWETSM GDHRAQAQAG DASWNPGVGH IPFFFGGGGG
     TSEDIVQPWY QAGKVPGALA ANVQTAAPAT RPMRVVPDVA MNGSLATSVD VAFTDGKYAH
     HDMGGTSVAA PEFAAVLADV KEASGHAVGF ANPSLYALNS SAFHDVTSRS GVTEGMWSNG
     DAGTLYQVGQ DTSLTATPGF DNATGLGSPA AGFEAALAAQ KGPAAPPQGG PAVTRVAGDD
     RYATAIAVSK KTFPKAGSAK AVVLATGSNF PDALAGVPLA KKLGAPLLLT PGNAADPRVV
     AEIHRVLAPG GKVYVLGGNA AVTPAVVSAL KVPAQRIAGD TRYTTSVAIA HALGDPSNVV
     LATGNGFADA LAAGPYASDV FTSDGPAAIL LTNDRIVPPA VYDYMRDHAG VLAAVGGQAV
     SAAAGTWAGH LTPLAGSDRF ETAAKVAATF PYAQNAGVAT GMQFADALTG AAMLAHENSP
     LLLTMPTSLP GFTRTALQGL AHSLAGGGSV DIFGGPVAVS NAVENAVAGA VGGHVVAP
//