ID A0A1Q7YNR3_9CHLR Unreviewed; 877 AA.
AC A0A1Q7YNR3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 13-SEP-2023, entry version 15.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=AUG13_06610 {ECO:0000313|EMBL:OLE56905.1};
OS Chloroflexi bacterium 13_1_20CM_2_59_7.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1805056 {ECO:0000313|EMBL:OLE56905.1, ECO:0000313|Proteomes:UP000186145};
RN [1] {ECO:0000313|EMBL:OLE56905.1, ECO:0000313|Proteomes:UP000186145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27843720;
RA Butterfield C.N., Li Z., Andeer P.F., Spaulding S., Thomas B.C., Singh A.,
RA Hettich R.L., Suttle K.B., Probst A.J., Tringe S.G., Northen T., Pan C.,
RA Banfield J.F.;
RT "Proteogenomic analyses indicate bacterial methylotrophy and archaeal
RT heterotrophy are prevalent below the grass root zone.";
RL PeerJ 4:E2687-E2687(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLE56905.1}.
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DR EMBL; MNKF01000122; OLE56905.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q7YNR3; -.
DR Proteomes; UP000186145; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 624..829
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 877 AA; 94606 MW; 6EA97D2A39F3674A CRC64;
MLISETTSSA LPVPKLRSGG RQPLLWAALA YTAGLSTGVH AWRPPLWWLV AWIVFAASAA
YLLRRRVRAA FALGLCALFI TGALTIQVRA PRDPGSSNLL EFADGQEVLV TAHVSAEGPL
HAEASGDVRQ RLDVETEQVT TGSQTFEIHS GLRVSFYGKK GKDESEEETS AVSARLFRYG
QRLRFPVKLY PPRNFRNPGA FDYQGYLAEN GIAALGSTKA TNVELLPGFT GSRAELWRTR
LHRSIVKRIH SLWPADEAAL VDAMLLGEES FMGRETLTEF QRTGTYHVLV VSGLKVGILS
LVTFWLLRRL RVGDLAASVV AVLLTVVYAV LTDVGAPVWR ATLMLALYLG ARLLYRQRAV
LNTIGGAALA LLILDPAAPF GASFQLSFMC VLIIAAVGLP LVERTTQPYS RALRHLDAVS
YDVALPPELA QFRLDLRMIA GRLARFLGKR MPLMVLGGIG RVLLISCEFL VISAVLQIGL
ALPMAYYFHR ANIVGLPANI LAVPLTEIIL VAAILAVALG YLSIALAKVP ALIAAAAIEA
TNGSVRWLGG LRIADARVPT PEFAVILFGA IALVLAMLLV RRRPSLAGAG LGVLAASAFW
ICAVPPRPQF RPGVLEVTAI DVGQGDSILL VSPQGRTLLV DAGGTPYWMH SELDIGEDVV
SPYLWSRGIA RLDAVAVTHA HADHIGGMGA ILANFHPHEL WLGIDSTEFE LKRLLEEANS
LGVGVASHKA GDTFELGGAK IRILAPEPNP DSGSRARRPN DESLAMKITY ADTSALLEGD
AERQTERQIA AEQPQADLLK VAHHGSATST IPELLAAVHP KFAVISVGTR NTYGHPRREV
LARLAESKVA TYRTDLNGAV TFYLDGKSVR PYVAGLR
//
