ID A0A1Q8CU19_9PSEU Unreviewed; 400 AA.
AC A0A1Q8CU19;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=3-oxoacyl-ACP synthase {ECO:0000313|EMBL:OLF17852.1};
GN ORFNames=BU204_09910 {ECO:0000313|EMBL:OLF17852.1};
OS Actinophytocola xanthii.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae.
OX NCBI_TaxID=1912961 {ECO:0000313|EMBL:OLF17852.1, ECO:0000313|Proteomes:UP000185596};
RN [1] {ECO:0000313|EMBL:OLF17852.1, ECO:0000313|Proteomes:UP000185596}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11-183 {ECO:0000313|EMBL:OLF17852.1,
RC ECO:0000313|Proteomes:UP000185596};
RA Wang W., Yuan L.;
RT "The draft genome sequence of Actinophytocola sp. 11-183.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis. {ECO:0000256|ARBA:ARBA00004792}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLF17852.1}.
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DR EMBL; MSIE01000014; OLF17852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q8CU19; -.
DR STRING; 1912961.BU204_09910; -.
DR OrthoDB; 9808669at2; -.
DR Proteomes; UP000185596; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Reference proteome {ECO:0000313|Proteomes:UP000185596};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..399
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 400 AA; 40538 MW; 3D8A5FB96FB6A41E CRC64;
MTGVGLVTPG GVGVRPSWQA ILAGRPTASR DTSLDGMSVD ITCRIPGFDA DALLGRRRAW
RLDRYVHLAL VAAREALTDA GLDPAAWDGT RVGVVMGNAL GGVGTFTAQH RTMLAEGADK
VSSLLIPMMG VNMVAGYLAM DCGAHGPNLV TTTACASATT AIGTARDLLR AGRCDIVLAG
GAEAGLSRPI VAGFTRMGAL SGRVDDPARA SRPFDRDRDG FVAAEGAGVL VLERPEHARA
RGARVLARVS GYGASADAHH ATAPDPAGTA AEAAIRAALA DAGLSASDVD HVNAHGTSTA
AGDAVEARVL RRVFPRRPAV TSVKGVTGHP LGAAGAIEAA CTALSISESV VPPTANLESQ
DPELDLDVVR GGPRTVPVAA ATSNSFGFGG QNAVLVLTAN
//
